Hong-sheng Lee

Taipei, TNQ, Taiwan

Last Updated: 09/26/2026

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Found 10 publications

Interleukin-6 induces the expression of connective tissue growth factor through the JAK2-dependent activation of STAT3 and p300 in human lung fibroblasts.

Interleukin-6 induces the expression of connective tissue growth factor through the JAK2-dependent activation of STAT3 and p300 in human lung fibroblasts.

Journal: Biochemical pharmacology

Published: March 23, 2026

MPT0E028, a pan-HDAC inhibitor, ameliorates bleomycin-induced pulmonary fibrosis by promoting AT2-to-AT1 differentiation through the ATM/AMPK/FoxO1 pathway.

MPT0E028, a pan-HDAC inhibitor, ameliorates bleomycin-induced pulmonary fibrosis by promoting AT2-to-AT1 differentiation through the ATM/AMPK/FoxO1 pathway.

Journal: Journal of biomedical science

Published: August 01, 2025

ET-1-induced CTGF expression is mediated by STAT3 activation through casein kinase 2α' and p300 but not casein kinase 2α in human lung fibroblasts.

ET-1-induced CTGF expression is mediated by STAT3 activation through casein kinase 2α' and p300 but not casein kinase 2α in human lung fibroblasts.

Journal: European journal of pharmacology

Published: July 25, 2025

Role of C/EBPβ/STAT3/AP-1 transcriptional complex formation in thrombin-induced connective tissue growth factor expression in human lung fibroblasts.

Role of C/EBPβ/STAT3/AP-1 transcriptional complex formation in thrombin-induced connective tissue growth factor expression in human lung fibroblasts.

Journal: European journal of pharmacology

Published: April 08, 2025

Involvement of ADAM17-dependent MUC1-CT activation in TGF-β-induced EZH2 expression in human lung fibroblasts and in ovalbumin-induced airway fibrosis in mice.

Involvement of ADAM17-dependent MUC1-CT activation in TGF-β-induced EZH2 expression in human lung fibroblasts and in ovalbumin-induced airway fibrosis in mice.

Journal: Biochemical pharmacology

Published: October 22, 2024

MPT0E028, a novel pan-HDAC inhibitor, prevents pulmonary fibrosis through inhibition of TGF-β-induced CTGF expression in human lung fibroblasts: Involvement of MKP-1 activation.

MPT0E028, a novel pan-HDAC inhibitor, prevents pulmonary fibrosis through inhibition of TGF-β-induced CTGF expression in human lung fibroblasts: Involvement of MKP-1 activation.

Journal: European journal of pharmacology

Published: March 06, 2024

Endothelin-1 induces connective tissue growth factor expression in human lung fibroblasts by disrupting HDAC2/Sin3A/MeCP2 corepressor complex.

Endothelin-1 induces connective tissue growth factor expression in human lung fibroblasts by disrupting HDAC2/Sin3A/MeCP2 corepressor complex.

Journal: Journal of biomedical science

Published: November 23, 2022

A Potent Histone Deacetylase Inhibitor MPT0E028 Mitigates Emphysema Severity via Components of the Hippo Signaling Pathway in an Emphysematous Mouse Model.

A Potent Histone Deacetylase Inhibitor MPT0E028 Mitigates Emphysema Severity via Components of the Hippo Signaling Pathway in an Emphysematous Mouse Model.

Journal: Frontiers in medicine

Published: October 13, 2021

Histone deacetylase 7 mediates endothelin-1-induced connective tissue growth factor expression in human lung fibroblasts through p300 and activator protein-1 activation.

Histone deacetylase 7 mediates endothelin-1-induced connective tissue growth factor expression in human lung fibroblasts through p300 and activator protein-1 activation.

Journal: Journal of biomedical science

Published: January 19, 2021

Synthesis and biological evaluation of phenothiazine derivative-containing hydroxamic acids as potent class II histone deacetylase inhibitors.

Synthesis and biological evaluation of phenothiazine derivative-containing hydroxamic acids as potent class II histone deacetylase inhibitors.

Journal: European journal of medicinal chemistry

Published: December 05, 2020

Showing 1-10 of 10

Last Updated: 09/26/2026