Hong Wan

279 Wenjing Road
Minhang, 200245, China

Last Updated: 09/26/2026

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Found 22 publications

The impact of dexamethasone on short- and long-term mortality in hospitalized COVID-19 patients: a retrospective study.

The impact of dexamethasone on short- and long-term mortality in hospitalized COVID-19 patients: a retrospective study.

Journal: BMC infectious diseases

Published: September 23, 2024

Enhancing drug-drug Interaction Prediction by Integrating Physiologically-Based Pharmacokinetic Model with Fraction Metabolized by CYP3A4.

Enhancing drug-drug Interaction Prediction by Integrating Physiologically-Based Pharmacokinetic Model with Fraction Metabolized by CYP3A4.

Journal: Expert opinion on drug metabolism & toxicology

Published: September 25, 2023

Preclinical evaluation of chemically reactive metabolites and mitigation of bioactivation in drug discovery.

Preclinical evaluation of chemically reactive metabolites and mitigation of bioactivation in drug discovery.

Journal: Drug discovery today

Published: December 20, 2022

Comparison of accuracy for hip-knee-ankle (HKA) angle by X-ray and knee motion analysis system and the relationships between HKA and gait posture.

Comparison of accuracy for hip-knee-ankle (HKA) angle by X-ray and knee motion analysis system and the relationships between HKA and gait posture.

Journal: BMC musculoskeletal disorders

Published: November 10, 2022

Discovery of novel spiro compound as RAF kinase inhibitor with in vitro potency against KRAS mutant cancer.

Discovery of novel spiro compound as RAF kinase inhibitor with in vitro potency against KRAS mutant cancer.

Journal: Bioorganic & medicinal chemistry letters

Published: November 29, 2021

Discovery of spiro amide SHR902275: A potent, selective, and efficacious RAF inhibitor targeting RAS mutant cancers.

Discovery of spiro amide SHR902275: A potent, selective, and efficacious RAF inhibitor targeting RAS mutant cancers.

Journal: European journal of medicinal chemistry

Published: October 10, 2021

Discovery of a novel RORγ antagonist with skin-restricted exposure for topical treatment of mild to moderate psoriasis.

Discovery of a novel RORγ antagonist with skin-restricted exposure for topical treatment of mild to moderate psoriasis.

Journal: Scientific reports

Published: January 20, 2021

Discovery of Hydroxyamidine Derivatives as Highly Potent, Selective Indoleamine-2,3-dioxygenase 1 Inhibitors.

Discovery of Hydroxyamidine Derivatives as Highly Potent, Selective Indoleamine-2,3-dioxygenase 1 Inhibitors.

Journal: ACS medicinal chemistry letters

Published: August 14, 2020

A High-Precision Magnetic-Assisted Heading Angle Calculation Method Based on a 1D Convolutional Neural Network (CNN) in a Complicated Magnetic Environment.

A High-Precision Magnetic-Assisted Heading Angle Calculation Method Based on a 1D Convolutional Neural Network (CNN) in a Complicated Magnetic Environment.

Journal: Micromachines

Published: June 14, 2020

Discovery of SHR0687, a Highly Potent and Peripheral Nervous System-Restricted KOR Agonist.

Discovery of SHR0687, a Highly Potent and Peripheral Nervous System-Restricted KOR Agonist.

Journal: ACS medicinal chemistry letters

Published: May 28, 2020

Improving the Heading Accuracy in Indoor Pedestrian Navigation Based on a Decision Tree and Kalman Filter.

Improving the Heading Accuracy in Indoor Pedestrian Navigation Based on a Decision Tree and Kalman Filter.

Journal: Sensors (Basel, Switzerland)

Published: January 20, 2020

Discovery of SHR1653, a Highly Potent and Selective OTR Antagonist with Improved Blood-Brain Barrier Penetration.

Discovery of SHR1653, a Highly Potent and Selective OTR Antagonist with Improved Blood-Brain Barrier Penetration.

Journal: ACS medicinal chemistry letters

Published: April 24, 2019

Showing 1-12 of 22

Last Updated: 09/26/2026