Hongtu Hu

238 Jiefang Rd
Wuhan, 430060, China

Last Updated: 09/26/2026

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Found 34 publications

Drug failure in diabetic kidney disease: translational barriers, target validation and trial de-risking strategies.

Drug failure in diabetic kidney disease: translational barriers, target validation and trial de-risking strategies.

Journal: Biochemical pharmacology
Published: July 06, 2026

Senescent repair memory in chronic disease: failed resolution as a driver of persistent organ dysfunction.

Senescent repair memory in chronic disease: failed resolution as a driver of persistent organ dysfunction.

Journal: Ageing research reviews
Published: July 02, 2026

Targeting LRH-1 alleviates diabetes-induced lipotoxicity in podocytes: role of PLIN5-mediated lipid droplet turnover.

Targeting LRH-1 alleviates diabetes-induced lipotoxicity in podocytes: role of PLIN5-mediated lipid droplet turnover.

Journal: Renal failure
Published: May 14, 2026

Metabolic control of renal cell fate in kidney disease: nutrient rewiring, senescence and fibrosis.

Metabolic control of renal cell fate in kidney disease: nutrient rewiring, senescence and fibrosis.

Journal: Metabolism: clinical and experimental
Published: May 14, 2026

SGLT2 inhibition attenuates diabetes-induced lipid nephrotoxicity by targeting SOAT1-mediated cholesterol metabolism in proximal tubular cells.

SGLT2 inhibition attenuates diabetes-induced lipid nephrotoxicity by targeting SOAT1-mediated cholesterol metabolism in proximal tubular cells.

Journal: Cellular signalling
Published: April 13, 2026

Sex differences in cardiovascular‑kidney‑metabolic syndrome: From pathogenesis to treatment response (Review).

Sex differences in cardiovascular‑kidney‑metabolic syndrome: From pathogenesis to treatment response (Review).

Journal: International journal of molecular medicine
Published: April 03, 2026

PLIN5 Protects Against Ang II-Induced Podocyte Lipotoxicity by Interacting With FKBP8 and Preserving Lipid Droplet-Mitochondria Contact.

PLIN5 Protects Against Ang II-Induced Podocyte Lipotoxicity by Interacting With FKBP8 and Preserving Lipid Droplet-Mitochondria Contact.

Journal: Cell proliferation
Published: January 31, 2026

Macrophage IgG Recycling Couples Glomerular IgG Accumulation to Podocyte Senescence in Obesity-Related Glomerulopathy.

Macrophage IgG Recycling Couples Glomerular IgG Accumulation to Podocyte Senescence in Obesity-Related Glomerulopathy.

Journal: Journal of the American Society of Nephrology : JASN
Published: January 03, 2026

ESRRA-ATG5-Mediated mitophagy enhances arginine metabolism to alleviate diabetic kidney disease.

ESRRA-ATG5-Mediated mitophagy enhances arginine metabolism to alleviate diabetic kidney disease.

Journal: Autophagy
Published: December 11, 2025

XIAP-ULK1-mediated mitophagy modulates carnitine metabolism to mitigate diabetic kidney disease.

XIAP-ULK1-mediated mitophagy modulates carnitine metabolism to mitigate diabetic kidney disease.

Journal: Autophagy
Published: October 26, 2025

Podocyte Metabolic Reprogramming and Targeted Therapy.

Podocyte Metabolic Reprogramming and Targeted Therapy.

Journal: Journal of the American Society of Nephrology : JASN
Published: October 13, 2025

ERRα-NOS2-mediated citrulline metabolism attenuates tubular epithelial cell senescence in diabetic kidney disease.

ERRα-NOS2-mediated citrulline metabolism attenuates tubular epithelial cell senescence in diabetic kidney disease.

Journal: Redox biology
Published: August 27, 2025
Showing 1-12 of 34

Last Updated: 09/26/2026