Hongyan L. Lin

227 South Chongqing Road
Shanghai, 200025, China

Last Updated: 09/26/2026

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Found 59 publications

Antifungal potential of naphthoquinone derivatives: screening of shikonin-based compounds and mechanistic insights into 5,8-dihydroxy-1,4-naphthoquinone against Candida albicans in vitro and in vivo.

Antifungal potential of naphthoquinone derivatives: screening of shikonin-based compounds and mechanistic insights into 5,8-dihydroxy-1,4-naphthoquinone against Candida albicans in vitro and in vivo.

Journal: Microbiology spectrum

Published: February 27, 2026

Integrated Network Pharmacology, Molecular Docking, and Experimental Validation for Uncovering the Pharmacodynamic Basis of Sanghuang against Human Pulmonary Fibrosis.

Integrated Network Pharmacology, Molecular Docking, and Experimental Validation for Uncovering the Pharmacodynamic Basis of Sanghuang against Human Pulmonary Fibrosis.

Journal: Combinatorial chemistry & high throughput screening

Published: February 16, 2026

An engineered ferritin nanocage co-delivery system for targeted hair cells protection and hearing loss attenuation.

An engineered ferritin nanocage co-delivery system for targeted hair cells protection and hearing loss attenuation.

Journal: Theranostics

Published: January 16, 2026

Corrigendum to "Click-chemistry mediated synthesis of podophyllotoxin triazole ether derivatives: Inhibiting human CRC tumor growth via dual targeting of AKT1 and tubulin" [Bioorg. Chem. 166 (2025) 109195].

Corrigendum to "Click-chemistry mediated synthesis of podophyllotoxin triazole ether derivatives: Inhibiting human CRC tumor growth via dual targeting of AKT1 and tubulin" [Bioorg. Chem. 166 (2025) 109195].

Journal: Bioorganic chemistry

Published: November 16, 2025

Click-chemistry mediated synthesis of podophyllotoxin triazole ether derivatives: Inhibiting human CRC tumor growth via dual targeting of AKT1 and tubulin.

Click-chemistry mediated synthesis of podophyllotoxin triazole ether derivatives: Inhibiting human CRC tumor growth via dual targeting of AKT1 and tubulin.

Journal: Bioorganic chemistry

Published: September 11, 2025

Non-additive synergistic effect on the efficient directed degradation of Leucaena leucocephala galactomannan via hydrogen peroxide and fumaric acid.

Non-additive synergistic effect on the efficient directed degradation of Leucaena leucocephala galactomannan via hydrogen peroxide and fumaric acid.

Journal: International journal of biological macromolecules

Published: July 09, 2025

Correction: Polygoni Multiflori Radix Praeparata polysaccharides enhance gut health and mitigate ischemic stroke by regulating SCFA and amino acid metabolism in gut microbiota.

Correction: Polygoni Multiflori Radix Praeparata polysaccharides enhance gut health and mitigate ischemic stroke by regulating SCFA and amino acid metabolism in gut microbiota.

Journal: Frontiers in pharmacology

Published: May 28, 2025

Novel Phenoxyacetic Acid (4-Aminophenoacetic Acid) Shikonin Ester Kills KRAS Mutant Colon Cancer Cells via Targeting the Akt Allosteric Site.

Novel Phenoxyacetic Acid (4-Aminophenoacetic Acid) Shikonin Ester Kills KRAS Mutant Colon Cancer Cells via Targeting the Akt Allosteric Site.

Journal: Chemical biology & drug design

Published: April 28, 2025

Pharmacokinetics, tissue distribution and metabolism study of 2,3,5,4'-Tetrahydroxystilbene-2-O-β-D-glucoside in a rat model of ischemic stroke using UHPLC‑Q‑TOF-MS/MS.

Pharmacokinetics, tissue distribution and metabolism study of 2,3,5,4'-Tetrahydroxystilbene-2-O-β-D-glucoside in a rat model of ischemic stroke using UHPLC‑Q‑TOF-MS/MS.

Journal: Journal of pharmaceutical and biomedical analysis

Published: March 29, 2025

Polygoni Multiflori Radix Praeparata polysaccharides enhance gut health and mitigate ischemic stroke by regulating SCFA and amino acid metabolism in gut microbiota.

Polygoni Multiflori Radix Praeparata polysaccharides enhance gut health and mitigate ischemic stroke by regulating SCFA and amino acid metabolism in gut microbiota.

Journal: Frontiers in pharmacology

Published: February 20, 2025

Design, synthesis and antitumor activity evaluation of novel modified 18β-glycyrrhetinate derivatives as PPARγ agonists.

Design, synthesis and antitumor activity evaluation of novel modified 18β-glycyrrhetinate derivatives as PPARγ agonists.

Journal: Bioorganic chemistry

Published: January 12, 2025

Shikonin Derivative Suppresses Colorectal Cancer Cells Growth via Reactive Oxygen Species-Mediated Mitochondrial Apoptosis and PI3K/AKT Pathway.

Shikonin Derivative Suppresses Colorectal Cancer Cells Growth via Reactive Oxygen Species-Mediated Mitochondrial Apoptosis and PI3K/AKT Pathway.

Journal: Chemistry & biodiversity

Published: December 11, 2024

Showing 1-12 of 59

Last Updated: 09/26/2026