Howard B. Broughton
Alcobendas, MD 28108, Spain
Last Updated: 09/26/2026
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Found 16 publications
Light-Regulated Agonists Spatiotemporally Activating the Vitamin D Receptor Mitigate Psoriasis-like Inflammation in Mice without Inducing Hypercalcemia.
Journal: ACS central science
Published: May 30, 2025
Author Correction: Crystal structure of active CDK4-cyclin D and mechanistic basis for abemaciclib efficacy.
Journal: NPJ breast cancer
Published: December 28, 2022
MAVEN: compound mechanism of action analysis and visualisation using transcriptomics and compound structure data in R/Shiny.
Journal: BMC bioinformatics
Published: September 27, 2022
Crystal structure of active CDK4-cyclin D and mechanistic basis for abemaciclib efficacy.
Journal: NPJ breast cancer
Published: April 11, 2022
Benchmarking causal reasoning algorithms for gene expression-based compound mechanism of action analysis.
Journal: BMC bioinformatics
Published: January 07, 2022
Defining Target Engagement Required for Efficacy In Vivo at the Retinoic Acid Receptor-Related Orphan Receptor C2 (RORγt).
Journal: Journal of medicinal chemistry
Published: April 14, 2021
The Angiopoietin-Like Protein 3 and 8 Complex Interacts with Lipoprotein Lipase and Induces LPL Cleavage.
Journal: ACS chemical biology
Published: March 03, 2021
A novel phage display vector for selection of target-specific peptides.
Journal: Protein engineering, design & selection : PEDS
Published: June 12, 2020
Integration of phage and yeast display platforms: A reliable and cost effective approach for binning of peptides as displayed on-phage.
Journal: PloS one
Published: October 02, 2019
A Decoupled Automation Platform for Hydrogen/Deuterium Exchange Mass Spectrometry Experiments.
Journal: Journal of the American Society for Mass Spectrometry
Published: June 10, 2019
High-throughput hydrogen bond strength calculation and its applications in optimizing drug ADME properties.
Journal: Future medicinal chemistry
Published: March 21, 2019
Deciphering Binding Interactions of IL-23R with HDX-MS: Mapping Protein and Macrocyclic Dodecapeptide Ligands.
Journal: ACS medicinal chemistry letters
Published: June 01, 2018
Last Updated: 09/26/2026