Hoyee Tsui

Utrecht, UT, Netherlands

Last Updated: 09/26/2026

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Found 15 publications

EPAS1 induction drives myocardial degeneration in desmoplakin-cardiomyopathy.

EPAS1 induction drives myocardial degeneration in desmoplakin-cardiomyopathy.

Journal: iScience

Published: August 22, 2024

Desmosomal protein degradation as an underlying cause of arrhythmogenic cardiomyopathy.

Desmosomal protein degradation as an underlying cause of arrhythmogenic cardiomyopathy.

Journal: Science translational medicine

Published: March 22, 2023

Therapeutic efficacy of AAV-mediated restoration of PKP2 in arrhythmogenic cardiomyopathy.

Therapeutic efficacy of AAV-mediated restoration of PKP2 in arrhythmogenic cardiomyopathy.

Journal: Nature cardiovascular research

Published: January 01, 2023

PITX2 induction leads to impaired cardiomyocyte function in arrhythmogenic cardiomyopathy.

PITX2 induction leads to impaired cardiomyocyte function in arrhythmogenic cardiomyopathy.

Journal: Stem cell reports

Published: August 29, 2022

Oxidized low-density lipoproteins as a novel risk factor and therapeutic target for ACM.

Oxidized low-density lipoproteins as a novel risk factor and therapeutic target for ACM.

Journal: EMBO molecular medicine

Published: July 15, 2021

Single-Cell Sequencing of the Healthy and Diseased Heart Reveals Cytoskeleton-Associated Protein 4 as a New Modulator of Fibroblasts Activation.

Single-Cell Sequencing of the Healthy and Diseased Heart Reveals Cytoskeleton-Associated Protein 4 as a New Modulator of Fibroblasts Activation.

Journal: Circulation

Published: November 10, 2017

The p21-activated kinase 1 (Pak1) signalling pathway in cardiac disease: from mechanistic study to therapeutic exploration.

The p21-activated kinase 1 (Pak1) signalling pathway in cardiac disease: from mechanistic study to therapeutic exploration.

Journal: British journal of pharmacology

Published: March 10, 2017

Stress-Activated Kinase Mitogen-Activated Kinase Kinase-7 Governs Epigenetics of Cardiac Repolarization for Arrhythmia Prevention.

Stress-Activated Kinase Mitogen-Activated Kinase Kinase-7 Governs Epigenetics of Cardiac Repolarization for Arrhythmia Prevention.

Journal: Circulation

Published: April 12, 2016

Smad3 Couples Pak1 With the Antihypertrophic Pathway Through the E3 Ubiquitin Ligase, Fbxo32.

Smad3 Couples Pak1 With the Antihypertrophic Pathway Through the E3 Ubiquitin Ligase, Fbxo32.

Journal: Hypertension (Dallas, Tex. : 1979)

Published: July 01, 2015

Novel insights into mechanisms for Pak1-mediated regulation of cardiac Ca(2+) homeostasis.

Novel insights into mechanisms for Pak1-mediated regulation of cardiac Ca(2+) homeostasis.

Journal: Frontiers in physiology

Published: December 20, 2014

Pak1 is required to maintain ventricular Ca²⁺ homeostasis and electrophysiological stability through SERCA2a regulation in mice.

Pak1 is required to maintain ventricular Ca²⁺ homeostasis and electrophysiological stability through SERCA2a regulation in mice.

Journal: Circulation. Arrhythmia and electrophysiology

Published: September 14, 2014

Mkk4 is a negative regulator of the transforming growth factor beta 1 signaling associated with atrial remodeling and arrhythmogenesis with age.

Mkk4 is a negative regulator of the transforming growth factor beta 1 signaling associated with atrial remodeling and arrhythmogenesis with age.

Journal: Journal of the American Heart Association

Published: April 12, 2014

Showing 1-12 of 15

Last Updated: 09/26/2026