Hu Zhou

State Key Laboratory Of Drug Research
Shanghai, China

Last Updated: 09/26/2026

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Found 44 publications

Phase separation-based HTS identifies cobimetinib as a YAP-TEAD inhibitor that suppresses hyperactivated YAP-induced cancer progression.

Phase separation-based HTS identifies cobimetinib as a YAP-TEAD inhibitor that suppresses hyperactivated YAP-induced cancer progression.

Journal: Science translational medicine

Published: April 22, 2026

ASB7 is a negative regulator of H3K9me3 homeostasis.

ASB7 is a negative regulator of H3K9me3 homeostasis.

Journal: Science (New York, N.Y.)

Published: May 29, 2025

Sertraline and Astemizole Enhance the Deubiquitinase Activity of USP7 by Binding to Its Switching Loop Region.

Sertraline and Astemizole Enhance the Deubiquitinase Activity of USP7 by Binding to Its Switching Loop Region.

Journal: Journal of medicinal chemistry

Published: February 25, 2025

Advancements in proteogenomics for preclinical targeted cancer therapy research.

Advancements in proteogenomics for preclinical targeted cancer therapy research.

Journal: Biophysics reports

Published: October 23, 2024

A positive-sense single-stranded RNA virus acquired a negative-sense open reading frame through recombination.

A positive-sense single-stranded RNA virus acquired a negative-sense open reading frame through recombination.

Journal: PLoS pathogens

Published: August 07, 2024

Zinc ions activate AKT and promote prostate cancer cell proliferation via disrupting AKT intramolecular interaction.

Zinc ions activate AKT and promote prostate cancer cell proliferation via disrupting AKT intramolecular interaction.

Journal: Oncogene

Published: June 20, 2024

Benzbromarone interferes with the interaction between Hsp90 and Aha1 by interacting with both of them.

Benzbromarone interferes with the interaction between Hsp90 and Aha1 by interacting with both of them.

Journal: Communications biology

Published: May 15, 2024

Uncovering PROTAC Sensitivity and Efficacy by Multidimensional Proteome Profiling: A Case for STAT3.

Uncovering PROTAC Sensitivity and Efficacy by Multidimensional Proteome Profiling: A Case for STAT3.

Journal: Journal of medicinal chemistry

Published: March 11, 2024

A novel capsid-XL32-derived adeno-associated virus serotype prompts retinal tropism and ameliorates choroidal neovascularization.

A novel capsid-XL32-derived adeno-associated virus serotype prompts retinal tropism and ameliorates choroidal neovascularization.

Journal: Biomaterials

Published: June 19, 2023

Proteogenomic characterization of small cell lung cancer identifies biological insights and subtype-specific therapeutic strategies.

Proteogenomic characterization of small cell lung cancer identifies biological insights and subtype-specific therapeutic strategies.

Journal: Cell

Published: December 19, 2022

Conjugation site characterization of antibody-drug conjugates using electron-transfer/higher-energy collision dissociation (EThcD).

Conjugation site characterization of antibody-drug conjugates using electron-transfer/higher-energy collision dissociation (EThcD).

Journal: Analytica chimica acta

Published: November 30, 2022

Selective activator of human ClpP triggers cell cycle arrest to inhibit lung squamous cell carcinoma.

Selective activator of human ClpP triggers cell cycle arrest to inhibit lung squamous cell carcinoma.

Journal: Nature communications

Published: November 23, 2022

Showing 1-12 of 44

Last Updated: 09/26/2026