Hua G. Xie

State Key Laboratory Of Drug Research
Shanghai, China

Last Updated: 09/26/2026

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Found 139 publications

Structure-guided discovery of 1H-pyrazolo[3,4-c]pyridin-3-amines as a novel class of hematopoietic progenitor kinase 1 (HPK1) inhibitors.

Structure-guided discovery of 1H-pyrazolo[3,4-c]pyridin-3-amines as a novel class of hematopoietic progenitor kinase 1 (HPK1) inhibitors.

Journal: European journal of medicinal chemistry
Published: May 09, 2026

Opportunities and challenges in the development of evolving EGFR inhibitors to overcome EGFR TKIs resistance.

Opportunities and challenges in the development of evolving EGFR inhibitors to overcome EGFR TKIs resistance.

Journal: Acta pharmacologica Sinica
Published: January 22, 2026

Design, synthesis and pharmacological evaluation of 3H-spiro[benzofuran-2,4'-piperidine] IRAK4 inhibitors for the treatment of diffuse large B-cell lymphoma.

Design, synthesis and pharmacological evaluation of 3H-spiro[benzofuran-2,4'-piperidine] IRAK4 inhibitors for the treatment of diffuse large B-cell lymphoma.

Journal: RSC medicinal chemistry
Published: January 12, 2026

pH-responsive dynamic organic nanocomposite hydrogels for enhanced local tumor combination therapy.

pH-responsive dynamic organic nanocomposite hydrogels for enhanced local tumor combination therapy.

Journal: Journal of biomaterials applications
Published: September 25, 2025

Ocular toxicity associated with antibody-drug conjugates in cancer therapy: a comprehensive review.

Ocular toxicity associated with antibody-drug conjugates in cancer therapy: a comprehensive review.

Journal: Frontiers in immunology
Published: September 03, 2025

DMPE: A Dual-Branch Molecular Property Encapsulation Framework With Kolmogorov-Arnold Networks.

DMPE: A Dual-Branch Molecular Property Encapsulation Framework With Kolmogorov-Arnold Networks.

Journal: Journal of computational chemistry
Published: September 02, 2025

Sphingosine-1-Phosphate Receptor 3 Confers Tumor Metastasis in Lung Cancer Resistant to Third-Generation EGFR Inhibitor.

Sphingosine-1-Phosphate Receptor 3 Confers Tumor Metastasis in Lung Cancer Resistant to Third-Generation EGFR Inhibitor.

Journal: MedComm
Published: July 25, 2025

The TaDof-2D-miR1832-TaP450-7A module regulates low-temperature-induced seed dormancy release in wheat.

The TaDof-2D-miR1832-TaP450-7A module regulates low-temperature-induced seed dormancy release in wheat.

Journal: Plant communications
Published: July 08, 2025

Targeting Cbl-b by a small molecular inhibitor potentiates T cell receptor signaling and suggests rational combination strategies.

Targeting Cbl-b by a small molecular inhibitor potentiates T cell receptor signaling and suggests rational combination strategies.

Journal: International immunopharmacology
Published: June 14, 2025

Discovery of TBK1Molecular Glue Degraders as a Potential Strategy for the Treatment of Autosomal Dominant Polycystic Kidney Disease (ADPKD).

Discovery of TBK1Molecular Glue Degraders as a Potential Strategy for the Treatment of Autosomal Dominant Polycystic Kidney Disease (ADPKD).

Journal: Journal of medicinal chemistry
Published: June 06, 2025

Causal Associations between Gastroesophageal Reflux Disease and Gastroduodenal Ulcer: A Two-sample Mendelian Randomisation Study.

Causal Associations between Gastroesophageal Reflux Disease and Gastroduodenal Ulcer: A Two-sample Mendelian Randomisation Study.

Journal: The American journal of the medical sciences
Published: June 03, 2025

TaGASR25 interacts with TaC3HC4 to modulate seed dormancy and germination in common wheat.

TaGASR25 interacts with TaC3HC4 to modulate seed dormancy and germination in common wheat.

Journal: The Plant journal : for cell and molecular biology
Published: May 31, 2025
Showing 1-12 of 139

Last Updated: 09/26/2026