Hudson W. Coates

Sydney, NSW, Australia

Last Updated: 09/26/2026

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Found 13 publications

Sensing of Cholesterol by Squalene Monooxygenase.

Sensing of Cholesterol by Squalene Monooxygenase.

Journal: Methods in molecular biology (Clifton, N.J.)

Published: February 24, 2025

The constitutively active form of a key cholesterol synthesis enzyme is lipid droplet-localized and upregulated in endometrial cancer tissues.

The constitutively active form of a key cholesterol synthesis enzyme is lipid droplet-localized and upregulated in endometrial cancer tissues.

Journal: The Journal of biological chemistry

Published: February 29, 2024

Asters: rising stars in the cholesterol universe.

Asters: rising stars in the cholesterol universe.

Journal: Nature metabolism

Published: January 16, 2023

Hypoxia truncates and constitutively activates the key cholesterol synthesis enzyme squalene monooxygenase.

Hypoxia truncates and constitutively activates the key cholesterol synthesis enzyme squalene monooxygenase.

Journal: eLife

Published: August 19, 2022

The Non Catalytic Protein ERG28 has a Functional Role in Cholesterol Synthesis and is Coregulated Transcriptionally.

The Non Catalytic Protein ERG28 has a Functional Role in Cholesterol Synthesis and is Coregulated Transcriptionally.

Journal: Journal of lipid research

Published: November 03, 2021

The mammalian cholesterol synthesis enzyme squalene monooxygenase is proteasomally truncated to a constitutively active form.

The mammalian cholesterol synthesis enzyme squalene monooxygenase is proteasomally truncated to a constitutively active form.

Journal: The Journal of biological chemistry

Published: October 16, 2020

Post-translational control of the long and winding road to cholesterol.

Post-translational control of the long and winding road to cholesterol.

Journal: The Journal of biological chemistry

Published: August 24, 2020

A key mammalian cholesterol synthesis enzyme, squalene monooxygenase, is allosterically stabilized by its substrate.

A key mammalian cholesterol synthesis enzyme, squalene monooxygenase, is allosterically stabilized by its substrate.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: March 15, 2020

Squalene monooxygenase: a journey to the heart of cholesterol synthesis.

Squalene monooxygenase: a journey to the heart of cholesterol synthesis.

Journal: Progress in lipid research

Published: March 03, 2020

A structure of human Scap bound to Insig-2 suggests how their interaction is regulated by sterols.

A structure of human Scap bound to Insig-2 suggests how their interaction is regulated by sterols.

Journal: Science (New York, N.Y.)

Published: February 08, 2020

A wolf in sheep's clothing: unmasking the lanosterol-induced degradation of HMG-CoA reductase.

A wolf in sheep's clothing: unmasking the lanosterol-induced degradation of HMG-CoA reductase.

Journal: Journal of lipid research

Published: August 30, 2019

Consulting prostate cancer cohort data uncovers transcriptional control: Regulation of the MARCH6 gene.

Consulting prostate cancer cohort data uncovers transcriptional control: Regulation of the MARCH6 gene.

Journal: Biochimica et biophysica acta. Molecular and cell biology of lipids

Published: February 19, 2019

Showing 1-12 of 13

Last Updated: 09/26/2026