Hugo R. De Jonge
Rotterdam, ZH, Netherlands
Last Updated: 09/26/2026
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Found 68 publications
Partially differentiated enterocytes in ileal and distal-colonic human F508del-CF-enteroids secrete fluid in response to forskolin and linaclotide.
Journal: bioRxiv : the preprint server for biology
Published: February 20, 2025
Partially differentiated ileal and distal-colonic human F508del-cystic fibrosis-enteroids secrete fluid in response to forskolin and linaclotide.
Journal: iScience
Published: July 30, 2024
Pro-inflammatory cytokines stimulate CFTR-dependent anion secretion in pancreatic ductal epithelium.
Pro-inflammatory cytokines stimulate CFTR-dependent anion secretion in pancreatic ductal epithelium.
Journal: Cellular & molecular biology letters
Published: October 24, 2023
CFTR function is impaired in a subset of patients with pancreatitis carrying rare CFTR variants.
Journal: Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]
Published: September 27, 2023
Targeted locus amplification reveals heterogeneity between and within CFTR genotypes and association with CFTR function in patient-derived intestinal organoids.
Journal: Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society
Published: December 23, 2022
Modeling bile duct ischemia and reoxygenation injury in human cholangiocyte organoids for screening of novel cholangio-protective agents.
Journal: EBioMedicine
Published: August 30, 2022
Theratyping of the Rare CFTR Variants E193K and R334W in Rectal Organoid-Derived Epithelial Monolayers.
Journal: Journal of personalized medicine
Published: March 07, 2022
Alterations of mucosa-attached microbiome and epithelial cell numbers in the cystic fibrosis small intestine with implications for intestinal disease.
Journal: Scientific reports
Published: December 06, 2021
Bicarbonate Transport in Cystic Fibrosis and Pancreatitis.
Journal: Cells
Published: November 20, 2021
Rescue of chloride and bicarbonate transport by elexacaftor-ivacaftor-tezacaftor in organoid-derived CF intestinal and cholangiocyte monolayers.
Journal: Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society
Published: August 20, 2021
A Potential Treatment of Congenital Sodium Diarrhea in Patients With Activating GUCY2C Mutations.
Journal: Clinical and translational gastroenterology
Published: May 26, 2021
Uridine attenuates obesity, ameliorates hepatic lipid accumulation and modifies the gut microbiota composition in mice fed with a high-fat diet.
Journal: Food & function
Published: February 02, 2021
Last Updated: 09/26/2026