Hugues B. De The

St. Louis Hospital
Paris, France

Last Updated: 09/26/2026

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Found 113 publications

Pml loss worsens NEK1-linked ALS and Pml induction drives NEK1 degradation, precluding disease onset.

Pml loss worsens NEK1-linked ALS and Pml induction drives NEK1 degradation, precluding disease onset.

Journal: The FEBS journal
Published: December 03, 2025

ATRA resistance conferred by a clustered subset of hotspot PML::RARA mutations enhancing basal repression rather than precluding transactivation.

ATRA resistance conferred by a clustered subset of hotspot PML::RARA mutations enhancing basal repression rather than precluding transactivation.

Journal: Haematologica
Published: November 25, 2025

PML-driven sumoylation of PML::RARA-bound repressors drives hematopoietic progenitor immortalization.

PML-driven sumoylation of PML::RARA-bound repressors drives hematopoietic progenitor immortalization.

Journal: The Journal of experimental medicine
Published: November 10, 2025

The Znf711-Phf8 complex functions as a transcriptional rheostat essential for neutrophil development.

The Znf711-Phf8 complex functions as a transcriptional rheostat essential for neutrophil development.

Journal: Haematologica
Published: October 30, 2025

Pierre Tiollais (1934-2024), a pioneer in genetic engineering with a lifelong commitment to the hepatitis B virus

Pierre Tiollais (1934-2024), a pioneer in genetic engineering with a lifelong commitment to the hepatitis B virus

Journal: Medecine sciences : M/S
Published: July 07, 2025

Immune intervention is dispensable for retinoic acid/ arsenic therapy of murine acute promyelocytic leukemia.

Immune intervention is dispensable for retinoic acid/ arsenic therapy of murine acute promyelocytic leukemia.

Journal: Haematologica
Published: June 26, 2025

Retinoic acid disrupts an NPM1c/ROS/SENP3/ARF oncogenic axis in acute myeloid leukemia.

Retinoic acid disrupts an NPM1c/ROS/SENP3/ARF oncogenic axis in acute myeloid leukemia.

Journal: Leukemia
Published: March 19, 2025

Conventional chemotherapy: millions of cures, unresolved therapeutic index.

Conventional chemotherapy: millions of cures, unresolved therapeutic index.

Journal: Nature reviews. Cancer
Published: November 15, 2024

Tripartite RAR fusions explain RA resistance.

Tripartite RAR fusions explain RA resistance.

Journal: Blood
Published: October 03, 2024

Acute Promyelocytic Leukemia, Retinoic Acid, and Arsenic: A Tale of Dualities.

Acute Promyelocytic Leukemia, Retinoic Acid, and Arsenic: A Tale of Dualities.

Journal: Cold Spring Harbor perspectives in medicine
Published: March 19, 2024

Creg1 Regulates Erythroid Development via TGF-β/Smad2-Klf1 Axis in Zebrafish.

Creg1 Regulates Erythroid Development via TGF-β/Smad2-Klf1 Axis in Zebrafish.

Journal: Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Published: March 18, 2024

Rnf111 has a pivotal role in regulating development of definitive hematopoietic stem and progenitor cells through the Smad2/3-Gcsfr/NO axis in zebrafish.

Rnf111 has a pivotal role in regulating development of definitive hematopoietic stem and progenitor cells through the Smad2/3-Gcsfr/NO axis in zebrafish.

Journal: Haematologica
Published: March 11, 2024
Showing 1-12 of 113

Last Updated: 09/26/2026