Huib Ovaa

Leiden, ZH, Netherlands

Last Updated: 09/26/2026

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Found 149 publications

USP8 controls proteostasis pathways in B cells and multiple myeloma.

USP8 controls proteostasis pathways in B cells and multiple myeloma.

Journal: Leukemia

Published: April 09, 2026

Leveraging Targeted Protein Degradation for G Protein-Coupled Receptors: The Development of CCR2 Molecular Degraders.

Leveraging Targeted Protein Degradation for G Protein-Coupled Receptors: The Development of CCR2 Molecular Degraders.

Journal: Journal of medicinal chemistry

Published: December 11, 2025

Site-directed multivalent conjugation of antibodies to ubiquitinated payloads.

Site-directed multivalent conjugation of antibodies to ubiquitinated payloads.

Journal: Nature biomedical engineering

Published: March 26, 2024

USP16 is an ISG15 cross-reactive deubiquitinase that targets pro-ISG15 and ISGylated proteins involved in metabolism.

USP16 is an ISG15 cross-reactive deubiquitinase that targets pro-ISG15 and ISGylated proteins involved in metabolism.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: December 06, 2023

Cellular Validation of a Chemically Improved Inhibitor Identifies Monoubiquitination on OTUB2.

Cellular Validation of a Chemically Improved Inhibitor Identifies Monoubiquitination on OTUB2.

Journal: ACS chemical biology

Published: August 29, 2023

In-Plate Chemical Synthesis of Isopeptide-Linked SUMOylated Peptide Fluorescence Polarization Reagents for High-Throughput Screening of SENP Preferences.

In-Plate Chemical Synthesis of Isopeptide-Linked SUMOylated Peptide Fluorescence Polarization Reagents for High-Throughput Screening of SENP Preferences.

Journal: Chembiochem : a European journal of chemical biology

Published: October 20, 2022

Chemical Toolkit for PARK7: Potent, Selective, and High-Throughput.

Chemical Toolkit for PARK7: Potent, Selective, and High-Throughput.

Journal: Journal of medicinal chemistry

Published: September 23, 2022

Neutron-encoded diubiquitins to profile linkage selectivity of deubiquitinating enzymes.

Neutron-encoded diubiquitins to profile linkage selectivity of deubiquitinating enzymes.

Journal: Nature communications

Published: June 08, 2022

Total Chemical Synthesis of a Functionalized GFP Nanobody.

Total Chemical Synthesis of a Functionalized GFP Nanobody.

Journal: Chembiochem : a European journal of chemical biology

Published: June 07, 2022

Inhibiting UCH-L5: Rational Design of a Cyclic Ubiquitin-Based Peptide Inhibitor.

Inhibiting UCH-L5: Rational Design of a Cyclic Ubiquitin-Based Peptide Inhibitor.

Journal: Frontiers in molecular biosciences

Published: January 31, 2022

Allosteric control of Ubp6 and the proteasome via a bidirectional switch.

Allosteric control of Ubp6 and the proteasome via a bidirectional switch.

Journal: Nature communications

Published: September 11, 2021

Development of Tyrphostin Analogues to Study Inhibition of the Mycobacterium tuberculosis Pup Proteasome System*.

Development of Tyrphostin Analogues to Study Inhibition of the Mycobacterium tuberculosis Pup Proteasome System*.

Journal: Chembiochem : a European journal of chemical biology

Published: July 08, 2021

Showing 1-12 of 149

Last Updated: 09/26/2026