Huilian Hua

Taizhou, China

Last Updated: 09/26/2026

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Found 8 publications

Taraxacum alleviates ulcerative colitis, accompanied by the modulation of gut microbiota and restoration of intestinal barrier integrity.

Taraxacum alleviates ulcerative colitis, accompanied by the modulation of gut microbiota and restoration of intestinal barrier integrity.

Journal: Frontiers in cellular and infection microbiology

Published: January 15, 2026

The material basis and mechanism of Xiaokening granules in the treatment of type 2 diabetes mellitus by AKT/mTOR/GSK3β.

The material basis and mechanism of Xiaokening granules in the treatment of type 2 diabetes mellitus by AKT/mTOR/GSK3β.

Journal: Fitoterapia

Published: May 05, 2025

RTA-408 attenuates the hepatic ischemia reperfusion injury in mice possibly by activating the Nrf2/HO-1 signaling pathway.

RTA-408 attenuates the hepatic ischemia reperfusion injury in mice possibly by activating the Nrf2/HO-1 signaling pathway.

Journal: Open life sciences

Published: October 10, 2024

The identification of potent dual-target monopolar spindle 1 (MPS1) and histone deacetylase 8 (HDAC8) inhibitors through pharmacophore modeling, molecular docking, molecular dynamics simulations, and biological evaluation.

The identification of potent dual-target monopolar spindle 1 (MPS1) and histone deacetylase 8 (HDAC8) inhibitors through pharmacophore modeling, molecular docking, molecular dynamics simulations, and biological evaluation.

Journal: Frontiers in pharmacology

Published: June 25, 2024

Discovery of novel and potent dual-targeting AXL/HDAC2 inhibitors for colorectal cancer treatment via structure-based pharmacophore modelling, virtual screening, and molecular docking, molecular dynamics simulation studies, and biological evaluation.

Discovery of novel and potent dual-targeting AXL/HDAC2 inhibitors for colorectal cancer treatment via structure-based pharmacophore modelling, virtual screening, and molecular docking, molecular dynamics simulation studies, and biological evaluation.

Journal: Journal of enzyme inhibition and medicinal chemistry

Published: December 22, 2023

Investigating the medicinal potential, material basis and mechanism of Polygoni Orientalis Fructus based on multi-technology integrated network pharmacology.

Investigating the medicinal potential, material basis and mechanism of Polygoni Orientalis Fructus based on multi-technology integrated network pharmacology.

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology

Published: February 23, 2021

Discovery of polypodiside as a Keap1-dependent Nrf2 activator attenuating oxidative stress and accumulation of extracellular matrix in glomerular mesangial cells under high glucose.

Discovery of polypodiside as a Keap1-dependent Nrf2 activator attenuating oxidative stress and accumulation of extracellular matrix in glomerular mesangial cells under high glucose.

Journal: Bioorganic & medicinal chemistry

Published: September 11, 2020

Discovery of a coumarin derivative as Nrf2 activator mitigating oxidative stress and fibrosis in mesangial cells under high glucose.

Discovery of a coumarin derivative as Nrf2 activator mitigating oxidative stress and fibrosis in mesangial cells under high glucose.

Journal: Bioorganic & medicinal chemistry letters

Published: June 09, 2020

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Last Updated: 09/26/2026