Humberto D. Gravina

Instituto Carlos Chagas/Fiocruz PR
Curitiba, PR, Brazil

Last Updated: 09/26/2026

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Found 11 publications

Context-dependent transcriptional and epigenetic reprogramming shapes neutrophil antimicrobial and immunoregulatory functions in tuberculosis.

Context-dependent transcriptional and epigenetic reprogramming shapes neutrophil antimicrobial and immunoregulatory functions in tuberculosis.

Journal: Tuberculosis (Edinburgh, Scotland)

Published: February 19, 2026

Extracellular Vesicles Favor Early Peripheral Immunosenescence Through Modulation of the Senescence-Associated Secretory Phenotype in HIV Infection.

Extracellular Vesicles Favor Early Peripheral Immunosenescence Through Modulation of the Senescence-Associated Secretory Phenotype in HIV Infection.

Journal: Aging cell

Published: April 07, 2025

Phenotypical Screening of an MMV Open Box Library and Identification of Compounds with Antiviral Activity against St. Louis Encephalitis Virus.

Phenotypical Screening of an MMV Open Box Library and Identification of Compounds with Antiviral Activity against St. Louis Encephalitis Virus.

Journal: Viruses

Published: October 14, 2023

COVID-19 inactivated and non-replicating viral vector vaccines induce regulatory training phenotype in human monocytes under epigenetic control.

COVID-19 inactivated and non-replicating viral vector vaccines induce regulatory training phenotype in human monocytes under epigenetic control.

Journal: Frontiers in cellular and infection microbiology

Published: April 05, 2023

Identification and characterization of the anti-SARS-CoV-2 activity of cationic amphiphilic steroidal compounds.

Identification and characterization of the anti-SARS-CoV-2 activity of cationic amphiphilic steroidal compounds.

Journal: Virulence

Published: June 23, 2022

Identification of insect-specific flaviviruses in areas of Brazil and Paraguay experiencing endemic arbovirus transmission and the description of a novel flavivirus infecting Sabethes belisarioi.

Identification of insect-specific flaviviruses in areas of Brazil and Paraguay experiencing endemic arbovirus transmission and the description of a novel flavivirus infecting Sabethes belisarioi.

Journal: Virology

Published: September 29, 2018

Upregulation of p38 pathway accelerates proliferation and migration of MDA-MB-231 breast cancer cells.

Upregulation of p38 pathway accelerates proliferation and migration of MDA-MB-231 breast cancer cells.

Journal: Oncology reports

Published: July 20, 2016

MyD88 Adapter-like (Mal)/TIRAP Is Required for Cytokine Production by Splenic Ly6CloTLR2hi but Not by Ly6ChiTLR2hi Monocytes during Trypanosoma cruzi Infection.

MyD88 Adapter-like (Mal)/TIRAP Is Required for Cytokine Production by Splenic Ly6CloTLR2hi but Not by Ly6ChiTLR2hi Monocytes during Trypanosoma cruzi Infection.

Journal: The Journal of biological chemistry

Published: March 28, 2016

DNA-Containing Immunocomplexes Promote Inflammasome Assembly and Release of Pyrogenic Cytokines by CD14+ CD16+ CD64high CD32low Inflammatory Monocytes from Malaria Patients.

DNA-Containing Immunocomplexes Promote Inflammasome Assembly and Release of Pyrogenic Cytokines by CD14+ CD16+ CD64high CD32low Inflammatory Monocytes from Malaria Patients.

Journal: mBio

Published: November 19, 2015

Differential use of TLR2 and TLR9 in the regulation of immune responses during the infection with Trypanosoma cruzi.

Differential use of TLR2 and TLR9 in the regulation of immune responses during the infection with Trypanosoma cruzi.

Journal: PloS one

Published: December 13, 2012

Neutrophil paralysis in Plasmodium vivax malaria.

Neutrophil paralysis in Plasmodium vivax malaria.

Journal: PLoS neglected tropical diseases

Published: February 17, 2012

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Last Updated: 09/26/2026