Hye-yeon Hwang
Suwon, Republic of Korea
Last Updated: 09/26/2026
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Found 16 publications
Structure-guided engineering of AI-derived adenine base editors for nuclear and mitochondrial DNA editing.
Journal: Nucleic acids research
Published: May 13, 2026
High-fidelity genome and prime editing enabled by the AI-designed openCRISPR-1.
Journal: Genome medicine
Published: July 22, 2025
Engineered virus-like particle-assembled Vegfa-targeting Cas9 ribonucleoprotein treatment alleviates neovascularization in wet age-related macular degeneration.
Journal: Genome biology
Published: February 05, 2025
Four germline POLH variants, including two found in skin tumors, impair DNA polymerase η function and cellular tolerance to UV radiation and cisplatin.
Journal: Chemico-biological interactions
Published: January 20, 2025
Engineered Sdd7 cytosine base editors with enhanced specificity.
Journal: Nature communications
Published: November 08, 2024
Precise editing of pathogenic nucleotide repeat expansions in iPSCs using paired prime editor.
Journal: Nucleic acids research
Published: January 09, 2024
CRISPR-based editing strategies to rectify EYA1 complex genomic rearrangement linked to haploinsufficiency.
Journal: Molecular therapy. Nucleic acids
Published: December 21, 2023
In vivo adenine base editing rescues adrenoleukodystrophy in a humanized mouse model.
Journal: Molecular therapy : the journal of the American Society of Gene Therapy
Published: November 06, 2023
Targeted genomic translocations and inversions generated using a paired prime editing strategy.
Journal: Molecular therapy : the journal of the American Society of Gene Therapy
Published: May 13, 2022
Expanded targeting scope of LbCas12a variants allows editing of multiple oncogenic mutations.
Journal: Molecular therapy. Nucleic acids
Published: April 20, 2022
DNA double-strand break-free CRISPR interference delays Huntington's disease progression in mice.
Journal: Communications biology
Published: January 18, 2022
Design of a RANK-Mimetic Peptide Inhibitor of Osteoclastogenesis with Enhanced RANKL-Binding Affinity.
Journal: Molecules and cells
Published: October 20, 2015
Last Updated: 09/26/2026