Hyojin Ko

Gwangju, Republic of Korea

Last Updated: 09/26/2026

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Found 13 publications

Synthesis and structure-activity relationships of quinolinone and quinoline-based P2X7 receptor antagonists and their anti-sphere formation activities in glioblastoma cells.

Synthesis and structure-activity relationships of quinolinone and quinoline-based P2X7 receptor antagonists and their anti-sphere formation activities in glioblastoma cells.

Journal: European journal of medicinal chemistry

Published: September 21, 2017

Discovery of Potent Antiallodynic Agents for Neuropathic Pain Targeting P2X3 Receptors.

Discovery of Potent Antiallodynic Agents for Neuropathic Pain Targeting P2X3 Receptors.

Journal: ACS chemical neuroscience

Published: March 22, 2017

Discovery and structure-activity relationship studies of quinolinone derivatives as potent IL-2 suppressive agents.

Discovery and structure-activity relationship studies of quinolinone derivatives as potent IL-2 suppressive agents.

Journal: Bioorganic & medicinal chemistry

Published: July 26, 2016

Potent Suppressive Effects of 1-Piperidinylimidazole Based Novel P2X7 Receptor Antagonists on Cancer Cell Migration and Invasion.

Potent Suppressive Effects of 1-Piperidinylimidazole Based Novel P2X7 Receptor Antagonists on Cancer Cell Migration and Invasion.

Journal: Journal of medicinal chemistry

Published: July 19, 2016

The discovery of 2,5-isomers of triazole-pyrrolopyrimidine as selective Janus kinase 2 (JAK2) inhibitors versus JAK1 and JAK3.

The discovery of 2,5-isomers of triazole-pyrrolopyrimidine as selective Janus kinase 2 (JAK2) inhibitors versus JAK1 and JAK3.

Journal: Bioorganic & medicinal chemistry

Published: July 11, 2016

2,3,4-Trihydroxybenzyl-hydrazide analogues as novel potent coxsackievirus B3 3C protease inhibitors.

2,3,4-Trihydroxybenzyl-hydrazide analogues as novel potent coxsackievirus B3 3C protease inhibitors.

Journal: European journal of medicinal chemistry

Published: October 29, 2015

Structure-activity relationship studies of pyrimidine-2,4-dione derivatives as potent P2X7 receptor antagonists.

Structure-activity relationship studies of pyrimidine-2,4-dione derivatives as potent P2X7 receptor antagonists.

Journal: European journal of medicinal chemistry

Published: June 08, 2015

Discovery of novel purine-based heterocyclic P2X7 receptor antagonists.

Discovery of novel purine-based heterocyclic P2X7 receptor antagonists.

Journal: Bioorganic chemistry

Published: April 23, 2015

Pheophorbide-a conjugates with cancer-targeting moieties for targeted photodynamic cancer therapy.

Pheophorbide-a conjugates with cancer-targeting moieties for targeted photodynamic cancer therapy.

Journal: Bioorganic & medicinal chemistry

Published: January 23, 2015

Discovery of novel 2,5-dioxoimidazolidine-based P2X(7) receptor antagonists as constrained analogues of KN62.

Discovery of novel 2,5-dioxoimidazolidine-based P2X(7) receptor antagonists as constrained analogues of KN62.

Journal: Journal of medicinal chemistry

Published: January 20, 2015

Solid-phase synthesis of quinolinone library.

Solid-phase synthesis of quinolinone library.

Journal: ACS combinatorial science

Published: December 02, 2014

Design and synthesis of potent and selective P2X₃ receptor antagonists derived from PPADS as potential pain modulators.

Design and synthesis of potent and selective P2X₃ receptor antagonists derived from PPADS as potential pain modulators.

Journal: European journal of medicinal chemistry

Published: August 16, 2013

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Last Updated: 09/26/2026