Iain J. Mcewan
Aberdeen, SCT, United Kingdom
Last Updated: 09/26/2026
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Found 42 publications
Deciphering the allosteric control of androgen receptor DNA binding by its disordered N-terminal domain.
Journal: Molecular and cellular endocrinology
Published: May 03, 2025
Polyglutamine expansion induced dynamic misfolding of androgen receptor.
Journal: Protein science : a publication of the Protein Society
Published: December 20, 2024
The androgen receptor amino-terminal domain: structure, function and therapeutic potential.
Journal: Endocrine oncology (Bristol, England)
Published: September 27, 2024
Ion mobility mass spectrometry unveils conformational effects of drug lead EPI-001 on the intrinsically disordered N-terminal domain of the androgen receptor.
Journal: Protein science : a publication of the Protein Society
Published: August 28, 2024
Synthesis and Evaluation of Small Molecule Inhibitors of the Androgen Receptor N-Terminal Domain.
Journal: ACS medicinal chemistry letters
Published: September 20, 2023
Mechanistic insights into steroid hormone-mediated regulation of the androgen receptor gene.
Journal: PloS one
Published: August 31, 2023
Current and emerging approaches to noncompetitive AR inhibition.
Journal: Medicinal research reviews
Published: December 06, 2022
Development of a High-Throughput Screening Assay for Small-Molecule Inhibitors of Androgen Receptor Splice Variants.
Journal: Assay and drug development technologies
Published: March 25, 2022
Topological dynamics of an intrinsically disordered N-terminal domain of the human androgen receptor.
Journal: Protein science : a publication of the Protein Society
Published: January 25, 2022
Eighty Years of Targeting Androgen Receptor Activity in Prostate Cancer: The Fight Goes on.
Journal: Cancers
Published: December 21, 2020
Orally Bioavailable Androgen Receptor Degrader, Potential Next-Generation Therapeutic for Enzalutamide-Resistant Prostate Cancer.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research
Published: May 06, 2019
Last Updated: 09/26/2026