
Last Updated: 09/26/2026
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Found 13 publications
Proteomic analysis reveals co-ordinated alterations in protein synthesis and degradation pathways in LRRK2 knockout mice.
Journal: Human molecular genetics
Published: April 03, 2018
Differences in Stability, Activity and Mutation Effects Between Human and Mouse Leucine-Rich Repeat Kinase 2.
Journal: Neurochemical research
Published: March 20, 2018
The G2385R risk factor for Parkinson's disease enhances CHIP-dependent intracellular degradation of LRRK2.
Journal: The Biochemical journal
Published: October 03, 2016
The function of orthologues of the human Parkinson's disease gene LRRK2 across species: implications for disease modelling in preclinical research.
Journal: The Biochemical journal
Published: January 27, 2016
Heterogeneity of leucine-rich repeat kinase 2 mutations: genetics, mechanisms and therapeutic implications.
Journal: Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics
Published: June 25, 2014
Unbiased screen for interactors of leucine-rich repeat kinase 2 supports a common pathway for sporadic and familial Parkinson disease.
Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: February 11, 2014
Aldehyde dehydrogenase 1 defines and protects a nigrostriatal dopaminergic neuron subpopulation.
Journal: The Journal of clinical investigation
Published: November 05, 2013
Hexokinase activity is required for recruitment of parkin to depolarized mitochondria.
Journal: Human molecular genetics
Published: August 22, 2013
Identification of protein phosphatase 1 as a regulator of the LRRK2 phosphorylation cycle.
Journal: The Biochemical journal
Published: August 14, 2013
mRNA expression, splicing and editing in the embryonic and adult mouse cerebral cortex.
Journal: Nature neuroscience
Published: November 15, 2012
The G2385R variant of leucine-rich repeat kinase 2 associated with Parkinson's disease is a partial loss-of-function mutation.
Journal: The Biochemical journal
Published: May 23, 2012
Last Updated: 09/26/2026