Ian Maclachlan
Burnaby, BC, Canada
Last Updated: 09/26/2026
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Found 9 publications
siRNA rescues nonhuman primates from advanced Marburg and Ravn virus disease.
Journal: The Journal of clinical investigation
Published: July 10, 2017
Rescue of non-human primates from advanced Sudan ebolavirus infection with lipid encapsulated siRNA.
Rescue of non-human primates from advanced Sudan ebolavirus infection with lipid encapsulated siRNA.
Journal: Nature microbiology
Published: April 14, 2016
Lipid nanoparticle siRNA treatment of Ebola-virus-Makona-infected nonhuman primates.
Journal: Nature
Published: January 27, 2015
Marburg virus infection in nonhuman primates: Therapeutic treatment by lipid-encapsulated siRNA.
Journal: Science translational medicine
Published: August 22, 2014
Antitumor effects in hepatocarcinoma of isoform-selective inhibition of HDAC2.
Journal: Cancer research
Published: June 25, 2014
Inhibition of hepatitis C virus in chimeric mice by short synthetic hairpin RNAs: sequence analysis of surviving virus shows added selective pressure of combination therapy.
Journal: Journal of virology
Published: January 31, 2014
Protection against lethal Marburg virus infection mediated by lipid encapsulated small interfering RNA.
Journal: The Journal of infectious diseases
Published: August 31, 2013
Minimal-length Synthetic shRNAs Formulated with Lipid Nanoparticles are Potent Inhibitors of Hepatitis C Virus IRES-linked Gene Expression in Mice.
Journal: Molecular therapy. Nucleic acids
Published: May 30, 2013
Formulated minimal-length synthetic small hairpin RNAs are potent inhibitors of hepatitis C virus in mice with humanized livers.
Journal: Gastroenterology
Published: May 22, 2013
Showing 1-9 of 9
Last Updated: 09/26/2026