Ian R. Humphreys

Ian R. Humphreys

Heath Park
Cardiff, WLS, United Kingdom

Last Updated: 09/26/2026

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Found 55 publications

Mitochondrial ABHD11 inhibition drives sterol metabolism to modulate T-cell effector function.

Mitochondrial ABHD11 inhibition drives sterol metabolism to modulate T-cell effector function.

Journal: Nature communications
Published: June 25, 2025

Cytomegalovirus-induced T cell responses accelerate Alzheimer's disease progression in mice.

Cytomegalovirus-induced T cell responses accelerate Alzheimer's disease progression in mice.

Journal: Brain : a journal of neurology
Published: April 11, 2025

Cytomegalovirus-induced peroxynitrite promotes virus entry and contributes to pathogenesis in a murine model of infection.

Cytomegalovirus-induced peroxynitrite promotes virus entry and contributes to pathogenesis in a murine model of infection.

Journal: mBio
Published: July 02, 2024

A pseudotyped adenovirus serotype 5 vector with serotype 49 fiber knob is an effective vector for vaccine and gene therapy applications.

A pseudotyped adenovirus serotype 5 vector with serotype 49 fiber knob is an effective vector for vaccine and gene therapy applications.

Journal: Molecular therapy. Methods & clinical development
Published: January 20, 2024

Acquisition of suppressive function by conventional T cells limits antitumor immunity upon Treg depletion.

Acquisition of suppressive function by conventional T cells limits antitumor immunity upon Treg depletion.

Journal: Science immunology
Published: December 15, 2023

Mucosal T-cell responses to chronic viral infections: Implications for vaccine design.

Mucosal T-cell responses to chronic viral infections: Implications for vaccine design.

Journal: Cellular & molecular immunology
Published: October 26, 2023

A targeted single mutation in influenza A virus universal epitope transforms immunogenicity and protective immunity via CD4+ T cell activation.

A targeted single mutation in influenza A virus universal epitope transforms immunogenicity and protective immunity via CD4+ T cell activation.

Journal: Cell reports
Published: September 10, 2023

Impact and outcomes after lymphaticovenous anastomosis for 150 cases of lymphoedema followed up over 24 months.

Impact and outcomes after lymphaticovenous anastomosis for 150 cases of lymphoedema followed up over 24 months.

Journal: Journal of plastic, reconstructive & aesthetic surgery : JPRAS
Published: March 20, 2023

A study protocol for a double-blind randomised placebo-controlled trial evaluating the efficacy of carrageenan nasal and throat spray for COVID-19 prophylaxis-ICE-COVID.

A study protocol for a double-blind randomised placebo-controlled trial evaluating the efficacy of carrageenan nasal and throat spray for COVID-19 prophylaxis-ICE-COVID.

Journal: Trials
Published: May 13, 2022

Inhibitory IL-10-producing CD4+ T cells are T-bet-dependent and facilitate cytomegalovirus persistence via coexpression of arginase-1.

Inhibitory IL-10-producing CD4+ T cells are T-bet-dependent and facilitate cytomegalovirus persistence via coexpression of arginase-1.

Journal: eLife
Published: April 01, 2022

An Analysis of Serological Response and Infection Outcomes Following Oxford-AstraZeneca (AZD1222) and Pfizer-BioNTech (mRNA BNT162b2) SARS-CoV-2 Vaccines in Kidney and Kidney-pancreas Transplants.

An Analysis of Serological Response and Infection Outcomes Following Oxford-AstraZeneca (AZD1222) and Pfizer-BioNTech (mRNA BNT162b2) SARS-CoV-2 Vaccines in Kidney and Kidney-pancreas Transplants.

Journal: Transplantation
Published: March 14, 2022

Mechanically Ventilated Patients Shed High-Titer Live Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) for Extended Periods From Both the Upper and Lower Respiratory Tract.

Mechanically Ventilated Patients Shed High-Titer Live Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) for Extended Periods From Both the Upper and Lower Respiratory Tract.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Published: December 22, 2021
Showing 1-12 of 55

Last Updated: 09/26/2026