Ibrahim Ince

Kaiser Wilhelm Allee
Leverkusen, NW 51373, Germany

Last Updated: 09/26/2026

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Found 24 publications

Coproporphyrin I PBPK model in the open systems pharmacology suite enables precise prediction of OATP 1B- mediated drug interactions through calibrated In vivo inhibition constants.

Coproporphyrin I PBPK model in the open systems pharmacology suite enables precise prediction of OATP 1B- mediated drug interactions through calibrated In vivo inhibition constants.

Journal: Frontiers in pharmacology

Published: March 11, 2026

Best Practices in Physiologically Based Pharmacokinetic (PBPK) Modeling.

Best Practices in Physiologically Based Pharmacokinetic (PBPK) Modeling.

Journal: CPT: pharmacometrics & systems pharmacology

Published: March 02, 2026

Open Systems Pharmacology Community Conference (OSP-CC) Proceedings 2025.

Open Systems Pharmacology Community Conference (OSP-CC) Proceedings 2025.

Journal: CPT: pharmacometrics & systems pharmacology

Published: December 07, 2025

Assessing Drug-Drug Interaction and Food Effect for BCS Class 2 Compound BI 730357 (Retinoic Acid-Related Orphan Receptor Gamma Antagonist, Bevurogant) Using a Physiology-Based Pharmacokinetics Modeling (PBPK) Approach with Semi-Mechanistic Absorption.

Assessing Drug-Drug Interaction and Food Effect for BCS Class 2 Compound BI 730357 (Retinoic Acid-Related Orphan Receptor Gamma Antagonist, Bevurogant) Using a Physiology-Based Pharmacokinetics Modeling (PBPK) Approach with Semi-Mechanistic Absorption.

Journal: Pharmaceutics

Published: December 20, 2024

Harnessing Open-Source Solutions: Insights From the First Open Systems Pharmacology (OSP) Community Conference.

Harnessing Open-Source Solutions: Insights From the First Open Systems Pharmacology (OSP) Community Conference.

Journal: CPT: pharmacometrics & systems pharmacology

Published: December 19, 2024

Applied physiologically-based pharmacokinetic modeling to assess uridine diphosphate-glucuronosyltransferase-mediated drug-drug interactions for Vericiguat.

Applied physiologically-based pharmacokinetic modeling to assess uridine diphosphate-glucuronosyltransferase-mediated drug-drug interactions for Vericiguat.

Journal: CPT: pharmacometrics & systems pharmacology

Published: June 13, 2023

Physiologically based pharmacokinetic (PBPK) modelling of oral drug absorption in older adults - an AGePOP review.

Physiologically based pharmacokinetic (PBPK) modelling of oral drug absorption in older adults - an AGePOP review.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences

Published: March 28, 2023

Nifurtimox for Treatment of Chagas Disease in Pediatric Patients: the Challenges of Applying Pharmacokinetic-Pharmacodynamic Principles to Dose Finding.

Nifurtimox for Treatment of Chagas Disease in Pediatric Patients: the Challenges of Applying Pharmacokinetic-Pharmacodynamic Principles to Dose Finding.

Journal: The AAPS journal

Published: April 19, 2022

Model-informed bridging of rivaroxaban doses for thromboprophylaxis in pediatric patients aged 9 years and older with congenital heart disease.

Model-informed bridging of rivaroxaban doses for thromboprophylaxis in pediatric patients aged 9 years and older with congenital heart disease.

Journal: CPT: pharmacometrics & systems pharmacology

Published: March 31, 2022

Population Pharmacokinetics of Nifurtimox in Adult and Pediatric Patients With Chagas Disease.

Population Pharmacokinetics of Nifurtimox in Adult and Pediatric Patients With Chagas Disease.

Journal: Journal of clinical pharmacology

Published: December 16, 2021

Population pharmacokinetic analysis of rivaroxaban in children and comparison to prospective physiologically-based pharmacokinetic predictions.

Population pharmacokinetic analysis of rivaroxaban in children and comparison to prospective physiologically-based pharmacokinetic predictions.

Journal: CPT: pharmacometrics & systems pharmacology

Published: April 01, 2021

Clinical investigation of the biopharmaceutical characteristics of nifurtimox tablets - Implications for quality control and application.

Clinical investigation of the biopharmaceutical characteristics of nifurtimox tablets - Implications for quality control and application.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences

Published: March 11, 2021

Showing 1-12 of 24

Last Updated: 09/26/2026