Ignacio Brouard

Santa Cruz De Tenerife, CN, Spain

Last Updated: 09/26/2026

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Found 18 publications

Structure-activity relationships reveal a 4-(2-pyridyl)chalcone as a potent cell death inducer.

Structure-activity relationships reveal a 4-(2-pyridyl)chalcone as a potent cell death inducer.

Journal: Chemico-biological interactions

Published: September 26, 2025

Guanidine Derivatives Containing the Chalcone Skeleton Are Potent Antiproliferative Compounds against Human Leukemia Cells.

Guanidine Derivatives Containing the Chalcone Skeleton Are Potent Antiproliferative Compounds against Human Leukemia Cells.

Journal: International journal of molecular sciences

Published: October 31, 2022

Structure-activity relationships reveal a 2-furoyloxychalcone as a potent cytotoxic and apoptosis inducer for human U-937 and HL-60 leukaemia cells.

Structure-activity relationships reveal a 2-furoyloxychalcone as a potent cytotoxic and apoptosis inducer for human U-937 and HL-60 leukaemia cells.

Journal: Bioorganic chemistry

Published: March 07, 2022

Chlorinated Guaiane-Type Sesquiterpene Lactones as Cytotoxic Agents against Human Tumor Cells.

Chlorinated Guaiane-Type Sesquiterpene Lactones as Cytotoxic Agents against Human Tumor Cells.

Journal: International journal of molecular sciences

Published: November 10, 2020

The synthetic flavanone 6-methoxy-2-(naphthalen-1-yl)chroman-4-one induces apoptosis and activation of the MAPK pathway in human U-937 leukaemia cells.

The synthetic flavanone 6-methoxy-2-(naphthalen-1-yl)chroman-4-one induces apoptosis and activation of the MAPK pathway in human U-937 leukaemia cells.

Journal: Bioorganic chemistry

Published: June 14, 2019

Centaurea microcarpa Coss. & Dur. (Asteraceae) extracts: New cyanogenic glucoside and other constituents.

Centaurea microcarpa Coss. & Dur. (Asteraceae) extracts: New cyanogenic glucoside and other constituents.

Journal: Natural product research

Published: November 18, 2018

6'-Benzyloxy-4-bromo-2'-hydroxychalcone is cytotoxic against human leukaemia cells and induces caspase-8- and reactive oxygen species-dependent apoptosis.

6'-Benzyloxy-4-bromo-2'-hydroxychalcone is cytotoxic against human leukaemia cells and induces caspase-8- and reactive oxygen species-dependent apoptosis.

Journal: Chemico-biological interactions

Published: July 25, 2018

3'-Hydroxy-3,4'-dimethoxyflavone-induced cell death in human leukaemia cells is dependent on caspases and reactive oxygen species and attenuated by the inhibition of JNK/SAPK.

3'-Hydroxy-3,4'-dimethoxyflavone-induced cell death in human leukaemia cells is dependent on caspases and reactive oxygen species and attenuated by the inhibition of JNK/SAPK.

Journal: Chemico-biological interactions

Published: December 21, 2017

3'-Hydroxy-3,4'-dimethoxyflavone blocks tubulin polymerization and is a potent apoptotic inducer in human SK-MEL-1 melanoma cells.

3'-Hydroxy-3,4'-dimethoxyflavone blocks tubulin polymerization and is a potent apoptotic inducer in human SK-MEL-1 melanoma cells.

Journal: Bioorganic & medicinal chemistry

Published: July 27, 2017

Antiproliferative activity and apoptosis induction by 3',4'-dibenzyloxyflavonol on human leukemia cells.

Antiproliferative activity and apoptosis induction by 3',4'-dibenzyloxyflavonol on human leukemia cells.

Journal: Chemico-biological interactions

Published: November 18, 2016

Sesquiterpenoids Isolated from Two Species of the Asteriscus Alliance.

Sesquiterpenoids Isolated from Two Species of the Asteriscus Alliance.

Journal: Journal of natural products

Published: May 05, 2016

Synthesis and effects on cell viability of flavonols and 3-methyl ether derivatives on human leukemia cells.

Synthesis and effects on cell viability of flavonols and 3-methyl ether derivatives on human leukemia cells.

Journal: European journal of medicinal chemistry

Published: January 10, 2014

Showing 1-12 of 18

Last Updated: 09/26/2026