Ignazia Tusa

Florence, 50134, Italy

Last Updated: 09/26/2026

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Found 33 publications

Development of a chaperone-mediated protein degrader targeting ERK5 that efficaciously reduces tumor growth.

Development of a chaperone-mediated protein degrader targeting ERK5 that efficaciously reduces tumor growth.

Journal: Cell communication and signaling : CCS

Published: September 04, 2025

Dual-Specificity Protein Phosphatases Targeting Extracellular Signal-Regulated Kinases: Friends or Foes in the Biology of Cancer?

Dual-Specificity Protein Phosphatases Targeting Extracellular Signal-Regulated Kinases: Friends or Foes in the Biology of Cancer?

Journal: International journal of molecular sciences

Published: June 11, 2025

The role of OSM/OSMRβ axis in shaping the tumor microenvironment favoring MASLD-related HCC immune evasion.

The role of OSM/OSMRβ axis in shaping the tumor microenvironment favoring MASLD-related HCC immune evasion.

Journal: Hepatology (Baltimore, Md.)

Published: April 17, 2025

The MEK5/ERK5 pathway promotes the activation of the Hedgehog/GLI signaling in melanoma cells.

The MEK5/ERK5 pathway promotes the activation of the Hedgehog/GLI signaling in melanoma cells.

Journal: Cellular oncology (Dordrecht, Netherlands)

Published: February 20, 2025

Liquid Crystalline Networks Hamper the Malignancy of Cancer Cells.

Liquid Crystalline Networks Hamper the Malignancy of Cancer Cells.

Journal: Advanced healthcare materials

Published: September 20, 2024

Ganglioside GD2 Contributes to a Stem-Like Phenotype in Intrahepatic Cholangiocarcinoma.

Ganglioside GD2 Contributes to a Stem-Like Phenotype in Intrahepatic Cholangiocarcinoma.

Journal: Liver international : official journal of the International Association for the Study of the Liver

Published: February 06, 2024

ERK5 mediates pro-tumorigenic phenotype in non-small lung cancer cells induced by PGE2.

ERK5 mediates pro-tumorigenic phenotype in non-small lung cancer cells induced by PGE2.

Journal: Biochimica et biophysica acta. Molecular cell research

Published: January 24, 2024

Importin subunit beta-1 mediates ERK5 nuclear translocation, and its inhibition synergizes with ERK5 kinase inhibitors in reducing cancer cell proliferation.

Importin subunit beta-1 mediates ERK5 nuclear translocation, and its inhibition synergizes with ERK5 kinase inhibitors in reducing cancer cell proliferation.

Journal: Molecular oncology

Published: October 03, 2023

Latent-Transforming Growth Factor β-Binding Protein 1/Transforming Growth Factor β1 Complex Drives Antitumoral Effects upon ERK5 Targeting in Melanoma.

Latent-Transforming Growth Factor β-Binding Protein 1/Transforming Growth Factor β1 Complex Drives Antitumoral Effects upon ERK5 Targeting in Melanoma.

Journal: The American journal of pathology

Published: September 15, 2023

Altered fatty acid metabolism rewires cholangiocarcinoma stemness features.

Altered fatty acid metabolism rewires cholangiocarcinoma stemness features.

Journal: JHEP reports : innovation in hepatology

Published: August 05, 2023

Pathophysiological Impact of the MEK5/ERK5 Pathway in Oxidative Stress.

Pathophysiological Impact of the MEK5/ERK5 Pathway in Oxidative Stress.

Journal: Cells

Published: January 11, 2023

Anti-β4 integrin autoantibodies in patients with mucous membrane pemphigoid: A retrospective analysis from a tertiary centre in Italy.

Anti-β4 integrin autoantibodies in patients with mucous membrane pemphigoid: A retrospective analysis from a tertiary centre in Italy.

Journal: Journal of the European Academy of Dermatology and Venereology : JEADV

Published: May 25, 2022

Showing 1-12 of 33

Last Updated: 09/26/2026