Ikuko Nakamae

Nara-shi, Japan

Last Updated: 09/26/2026

Save publications for later

Sign Up

Not sure about your diagnosis?

Check Your Symptoms

Found 12 publications

Pentagamavunone-1 targets excessive MYCN/NCYM expression mediated by mitotic arrest to suppress hepatocellular carcinoma proliferation.

Pentagamavunone-1 targets excessive MYCN/NCYM expression mediated by mitotic arrest to suppress hepatocellular carcinoma proliferation.

Journal: Cancer gene therapy

Published: March 26, 2025

The Combination of Sorafenib and PGV-1 Inhibits the Proliferation of Hepatocellular Carcinoma Through c-Myc Suppression in an Additive Manner: In Vitro Studies.

The Combination of Sorafenib and PGV-1 Inhibits the Proliferation of Hepatocellular Carcinoma Through c-Myc Suppression in an Additive Manner: In Vitro Studies.

Journal: Advances in pharmacological and pharmaceutical sciences

Published: November 11, 2023

Pentagamavunone-1 inhibits aggressive breast cancer cell proliferation through mitotic catastrophe and ROS-mediated activities: in vitro and in vivo studies.

Pentagamavunone-1 inhibits aggressive breast cancer cell proliferation through mitotic catastrophe and ROS-mediated activities: in vitro and in vivo studies.

Journal: Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society

Published: May 12, 2023

Preclinical evaluation of pentagamavunone-1 as monotherapy and combination therapy for pancreatic cancer in multiple xenograft models.

Preclinical evaluation of pentagamavunone-1 as monotherapy and combination therapy for pancreatic cancer in multiple xenograft models.

Journal: Scientific reports

Published: September 30, 2022

Stabilization of fatty acid synthesis enzyme acetyl-CoA carboxylase 1 suppresses acute myeloid leukemia development.

Stabilization of fatty acid synthesis enzyme acetyl-CoA carboxylase 1 suppresses acute myeloid leukemia development.

Journal: The Journal of clinical investigation

Published: June 19, 2020

Curcumin Derivatives Verify the Essentiality of ROS Upregulation in Tumor Suppression.

Curcumin Derivatives Verify the Essentiality of ROS Upregulation in Tumor Suppression.

Journal: Molecules (Basel, Switzerland)

Published: October 04, 2019

Pentagamavunon-1 (PGV-1) inhibits ROS metabolic enzymes and suppresses tumor cell growth by inducing M phase (prometaphase) arrest and cell senescence.

Pentagamavunon-1 (PGV-1) inhibits ROS metabolic enzymes and suppresses tumor cell growth by inducing M phase (prometaphase) arrest and cell senescence.

Journal: Scientific reports

Published: February 04, 2019

Anti-proliferative and Anti-metastatic Potential of Curcumin Analogue, Pentagamavunon-1 (PGV-1), Toward Highly Metastatic Breast Cancer Cells in Correlation with ROS Generation.

Anti-proliferative and Anti-metastatic Potential of Curcumin Analogue, Pentagamavunon-1 (PGV-1), Toward Highly Metastatic Breast Cancer Cells in Correlation with ROS Generation.

Journal: Advanced pharmaceutical bulletin

Published: October 04, 2018

Curcumin targets multiple enzymes involved in the ROS metabolic pathway to suppress tumor cell growth.

Curcumin targets multiple enzymes involved in the ROS metabolic pathway to suppress tumor cell growth.

Journal: Scientific reports

Published: September 14, 2017

Myeloid leukemia factor 1 stabilizes tumor suppressor C/EBPα to prevent Trib1-driven acute myeloid leukemia.

Myeloid leukemia factor 1 stabilizes tumor suppressor C/EBPα to prevent Trib1-driven acute myeloid leukemia.

Journal: Blood advances

Published: March 22, 2017

Homozygous inactivation of CHEK2 is linked to a familial case of multiple primary lung cancer with accompanying cancers in other organs.

Homozygous inactivation of CHEK2 is linked to a familial case of multiple primary lung cancer with accompanying cancers in other organs.

Journal: Cold Spring Harbor molecular case studies

Published: December 01, 2016

COP1 targets C/EBPα for degradation and induces acute myeloid leukemia via Trib1.

COP1 targets C/EBPα for degradation and induces acute myeloid leukemia via Trib1.

Journal: Blood

Published: July 26, 2013

Showing 1-12 of 12

Last Updated: 09/26/2026