Ioannis Galdadas

Geneve, GE, Switzerland

Last Updated: 09/26/2026

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Found 16 publications

Application of Language Models for the Analysis of Adverse Drug Events in Pharmaceutical Research and Development: Scoping Review.

Application of Language Models for the Analysis of Adverse Drug Events in Pharmaceutical Research and Development: Scoping Review.

Journal: JMIR AI

Published: May 23, 2025

Piecing together the structure of epidermal growth factor receptor complexes: a journey from crystals to cells and its impact on cancer therapy.

Piecing together the structure of epidermal growth factor receptor complexes: a journey from crystals to cells and its impact on cancer therapy.

Journal: Philosophical transactions of the Royal Society of London. Series B, Biological sciences

Published: March 20, 2025

Architecture of the MKK6-p38α complex defines the basis of MAPK specificity and activation.

Architecture of the MKK6-p38α complex defines the basis of MAPK specificity and activation.

Journal: Science (New York, N.Y.)

Published: September 14, 2023

Drug-resistant EGFR mutations promote lung cancer by stabilizing interfaces in ligand-free kinase-active EGFR oligomers.

Drug-resistant EGFR mutations promote lung cancer by stabilizing interfaces in ligand-free kinase-active EGFR oligomers.

Journal: Nature communications

Published: July 05, 2023

The action of physiological and synthetic steroids on the calcium channel CatSper in human sperm.

The action of physiological and synthetic steroids on the calcium channel CatSper in human sperm.

Journal: Frontiers in cell and developmental biology

Published: May 12, 2023

Revealing druggable cryptic pockets in the Nsp1 of SARS-CoV-2 and other β-coronaviruses by simulations and crystallography.

Revealing druggable cryptic pockets in the Nsp1 of SARS-CoV-2 and other β-coronaviruses by simulations and crystallography.

Journal: eLife

Published: June 17, 2022

Design, Synthesis, and Anticancer Activity of a Selenium-Containing Galectin-3 and Galectin-9N Inhibitor.

Design, Synthesis, and Anticancer Activity of a Selenium-Containing Galectin-3 and Galectin-9N Inhibitor.

Journal: International journal of molecular sciences

Published: January 18, 2022

The effect of S427F mutation on RXRα activity depends on its dimeric partner.

The effect of S427F mutation on RXRα activity depends on its dimeric partner.

Journal: Chemical science

Published: August 17, 2021

Allosteric communication in class A β-lactamases occurs via cooperative coupling of loop dynamics.

Allosteric communication in class A β-lactamases occurs via cooperative coupling of loop dynamics.

Journal: eLife

Published: January 14, 2021

Structural basis of the effect of activating mutations on the EGF receptor.

Structural basis of the effect of activating mutations on the EGF receptor.

Journal: eLife

Published: December 16, 2020

Concurrent mutations in RNA-dependent RNA polymerase and spike protein emerged as the epidemiologically most successful SARS-CoV-2 variant.

Concurrent mutations in RNA-dependent RNA polymerase and spike protein emerged as the epidemiologically most successful SARS-CoV-2 variant.

Journal: Scientific reports

Published: October 14, 2020

Unravelling the effect of the E545K mutation on PI3Kα kinase.

Unravelling the effect of the E545K mutation on PI3Kα kinase.

Journal: Chemical science

Published: November 20, 2019

Showing 1-12 of 16

Last Updated: 09/26/2026