Iona J. Davies

London, ENG, United Kingdom

Last Updated: 09/26/2026

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Found 16 publications

Opposing GIPR brainstem circuits differentially control feeding behaviour.

Opposing GIPR brainstem circuits differentially control feeding behaviour.

Journal: bioRxiv : the preprint server for biology

Published: July 17, 2026

The Paradox and Future of GLP-1/GIP Combination Therapies: Efficacy and Mechanisms.

The Paradox and Future of GLP-1/GIP Combination Therapies: Efficacy and Mechanisms.

Journal: Annual review of nutrition

Published: May 21, 2026

Metabolic state determines the brain and direct islet effects of liraglutide on enhanced insulin secretion.

Metabolic state determines the brain and direct islet effects of liraglutide on enhanced insulin secretion.

Journal: Diabetologia

Published: September 27, 2025

A metabolic comparison of GIPR agonism versus GIPR antagonism in male mice.

A metabolic comparison of GIPR agonism versus GIPR antagonism in male mice.

Journal: Diabetes, obesity & metabolism

Published: August 04, 2025

Spatially diffuse cAMP signalling with oppositely biased GLP-1 receptor agonists in β-cells despite differences in receptor localisation.

Spatially diffuse cAMP signalling with oppositely biased GLP-1 receptor agonists in β-cells despite differences in receptor localisation.

Journal: Molecular metabolism

Published: July 30, 2025

The physiological impact of an N-terminal Halo-tag on glucose-dependent insulinotropic polypeptide receptor function in mice.

The physiological impact of an N-terminal Halo-tag on glucose-dependent insulinotropic polypeptide receptor function in mice.

Journal: Diabetes, obesity & metabolism

Published: December 18, 2024

Chronic GIPR agonism results in pancreatic islet GIPR functional desensitisation.

Chronic GIPR agonism results in pancreatic islet GIPR functional desensitisation.

Journal: Molecular metabolism

Published: November 11, 2024

Dietary protein defends lean mass and maintains the metabolic benefits of glucagon receptor agonism in mice.

Dietary protein defends lean mass and maintains the metabolic benefits of glucagon receptor agonism in mice.

Journal: Molecular metabolism

Published: June 11, 2024

Selective remodelling of the adipose niche in obesity and weight loss.

Selective remodelling of the adipose niche in obesity and weight loss.

Journal: Nature

Published: May 31, 2024

Chronic treatment with glucagon-like peptide-1 and glucagon receptor co-agonist causes weight loss-independent improvements in hepatic steatosis in mice with diet-induced obesity.

Chronic treatment with glucagon-like peptide-1 and glucagon receptor co-agonist causes weight loss-independent improvements in hepatic steatosis in mice with diet-induced obesity.

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Published: May 03, 2024

Adaptive infusion of a glucagon-like peptide-1/glucagon receptor co-agonist G3215, in adults with overweight or obesity: Results from a phase 1 randomized clinical trial.

Adaptive infusion of a glucagon-like peptide-1/glucagon receptor co-agonist G3215, in adults with overweight or obesity: Results from a phase 1 randomized clinical trial.

Journal: Diabetes, obesity & metabolism

Published: November 17, 2023

Design of novel therapeutics targeting the glucose-dependent insulinotropic polypeptide receptor (GIPR) to aid weight loss.

Design of novel therapeutics targeting the glucose-dependent insulinotropic polypeptide receptor (GIPR) to aid weight loss.

Journal: Expert opinion on drug discovery

Published: May 08, 2023

Showing 1-12 of 16

Last Updated: 09/26/2026