Iqra Ajmal

Dongguan, 523000, China

Last Updated: 09/26/2026

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Found 17 publications

Advanced strategies to enhance the safety, persistence, and efficacy of CAR-T cells in solid tumors.

Advanced strategies to enhance the safety, persistence, and efficacy of CAR-T cells in solid tumors.

Journal: Frontiers in immunology
Published: February 19, 2026

KLRG1 silencing increases the efficacy of CAR NK cell therapy against colon cancer via SHP-2/ZAP-70/NF-κB signal pathway.

KLRG1 silencing increases the efficacy of CAR NK cell therapy against colon cancer via SHP-2/ZAP-70/NF-κB signal pathway.

Journal: Journal of translational medicine
Published: January 07, 2026

Overexpression of HIF-1α via small activating RNA enhances CAR-T cell function in hypoxic microenvironments.

Overexpression of HIF-1α via small activating RNA enhances CAR-T cell function in hypoxic microenvironments.

Journal: Pharmacological research
Published: January 03, 2026

TIPE2 knockdown enhances the anti-tumor efficacy of NKG2D CAR-T cells against pancreatic cancer via activating NF-κb signaling pathway.

TIPE2 knockdown enhances the anti-tumor efficacy of NKG2D CAR-T cells against pancreatic cancer via activating NF-κb signaling pathway.

Journal: Journal of translational medicine
Published: November 11, 2025

Chimeric cytokine receptor TGF-β RⅡ/IL-21R improves CAR-NK cell function by reversing the immunosuppressive tumor microenvironment of gastric cancer.

Chimeric cytokine receptor TGF-β RⅡ/IL-21R improves CAR-NK cell function by reversing the immunosuppressive tumor microenvironment of gastric cancer.

Journal: Pharmacological research
Published: October 28, 2024

A novel strategy of co-expressing CXCR5 and IL-7 enhances CAR-T cell effectiveness in osteosarcoma.

A novel strategy of co-expressing CXCR5 and IL-7 enhances CAR-T cell effectiveness in osteosarcoma.

Journal: Frontiers in immunology
Published: July 17, 2024

Modulating Cholesterol Metabolism via ACAT1 Knockdown Enhances Anti-B-Cell Lymphoma Activities of CD19-Specific Chimeric Antigen Receptor T Cells by Improving the Cell Activation and Proliferation.

Modulating Cholesterol Metabolism via ACAT1 Knockdown Enhances Anti-B-Cell Lymphoma Activities of CD19-Specific Chimeric Antigen Receptor T Cells by Improving the Cell Activation and Proliferation.

Journal: Cells
Published: January 19, 2024

shRNA-mediated gene silencing of HDAC11 empowers CAR-T cells against prostate cancer.

shRNA-mediated gene silencing of HDAC11 empowers CAR-T cells against prostate cancer.

Journal: Frontiers in immunology
Published: January 12, 2024

Intrinsic ADRB2 inhibition improves CAR-T cell therapy efficacy against prostate cancer.

Intrinsic ADRB2 inhibition improves CAR-T cell therapy efficacy against prostate cancer.

Journal: Molecular therapy : the journal of the American Society of Gene Therapy
Published: January 07, 2024

Co-expression of IL-4/IL-15-based inverted cytokine receptor in CAR-T cells overcomes IL-4 signaling in immunosuppressive pancreatic tumor microenvironment.

Co-expression of IL-4/IL-15-based inverted cytokine receptor in CAR-T cells overcomes IL-4 signaling in immunosuppressive pancreatic tumor microenvironment.

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Published: July 29, 2023

β2-Adrenergic Receptor Mediated Inhibition of T Cell Function and Its Implications for CAR-T Cell Therapy.

β2-Adrenergic Receptor Mediated Inhibition of T Cell Function and Its Implications for CAR-T Cell Therapy.

Journal: International journal of molecular sciences
Published: July 16, 2023

Hyperglycemia-associated Alzheimer's-like symptoms and other behavioral effects attenuated by Plumeria obtusa L. Extract in alloxan-induced diabetic rats.

Hyperglycemia-associated Alzheimer's-like symptoms and other behavioral effects attenuated by Plumeria obtusa L. Extract in alloxan-induced diabetic rats.

Journal: Frontiers in pharmacology
Published: October 23, 2022
Showing 1-12 of 17

Last Updated: 09/26/2026