Irati Macaya

Pamplona, NC, Spain

Last Updated: 09/26/2026

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Found 20 publications

Anticancer activity of RAS-GTP inhibition in cholangiocarcinoma.

Anticancer activity of RAS-GTP inhibition in cholangiocarcinoma.

Journal: Cancer cell
Published: June 18, 2025

Trametinib sensitizes KRAS-mutant lung adenocarcinoma tumors to PD-1/PD-L1 axis blockade via Id1 downregulation.

Trametinib sensitizes KRAS-mutant lung adenocarcinoma tumors to PD-1/PD-L1 axis blockade via Id1 downregulation.

Journal: Molecular cancer
Published: November 15, 2023

Correction: The phospholipid transporter PITPNC1 links KRAS to MYC to prevent autophagy in lung and pancreatic cancer.

Correction: The phospholipid transporter PITPNC1 links KRAS to MYC to prevent autophagy in lung and pancreatic cancer.

Journal: Molecular cancer
Published: June 16, 2023

RhoA downregulation in the murine intestinal epithelium results in chronic Wnt activation and increased tumorigenesis.

RhoA downregulation in the murine intestinal epithelium results in chronic Wnt activation and increased tumorigenesis.

Journal: iScience
Published: April 26, 2023

Signature-driven repurposing of Midostaurin for combination with MEK1/2 and KRASG12C inhibitors in lung cancer.

Signature-driven repurposing of Midostaurin for combination with MEK1/2 and KRASG12C inhibitors in lung cancer.

Journal: Nature communications
Published: December 13, 2022

The phospholipid transporter PITPNC1 links KRAS to MYC to prevent autophagy in lung and pancreatic cancer.

The phospholipid transporter PITPNC1 links KRAS to MYC to prevent autophagy in lung and pancreatic cancer.

Journal: Molecular cancer
Published: October 18, 2022

Myosin Vb as a tumor suppressor gene in intestinal cancer.

Myosin Vb as a tumor suppressor gene in intestinal cancer.

Journal: Oncogene
Published: June 05, 2022

LAMC2 Regulates Key Transcriptional and Targetable Effectors to Support Pancreatic Cancer Growth.

LAMC2 Regulates Key Transcriptional and Targetable Effectors to Support Pancreatic Cancer Growth.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research
Published: March 14, 2022

Complement C5a induces the formation of neutrophil extracellular traps by myeloid-derived suppressor cells to promote metastasis.

Complement C5a induces the formation of neutrophil extracellular traps by myeloid-derived suppressor cells to promote metastasis.

Journal: Cancer letters
Published: October 22, 2021

FOSL1 promotes cholangiocarcinoma via transcriptional effectors that could be therapeutically targeted.

FOSL1 promotes cholangiocarcinoma via transcriptional effectors that could be therapeutically targeted.

Journal: Journal of hepatology
Published: July 30, 2020

Liver Kinase B1 (LKB1) Loss Has its p-ERKs: ERK Inactivation as a Vulnerability in NSCLC With LKB1 Mutations.

Liver Kinase B1 (LKB1) Loss Has its p-ERKs: ERK Inactivation as a Vulnerability in NSCLC With LKB1 Mutations.

Journal: Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer
Published: November 19, 2019

Short-term starvation reduces IGF-1 levels to sensitize lung tumors to PD-1 immune checkpoint blockade.

Short-term starvation reduces IGF-1 levels to sensitize lung tumors to PD-1 immune checkpoint blockade.

Journal: Nature cancer
Published: August 30, 2019
Showing 1-12 of 20

Last Updated: 09/26/2026