Irena Manov

Haifa, HA, Israel

Last Updated: 09/26/2026

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Found 16 publications

Sengers syndrome caused by biallelic TIMM29 variants and RNAi silencing in Drosophila orthologue recapitulates the human phenotype.

Sengers syndrome caused by biallelic TIMM29 variants and RNAi silencing in Drosophila orthologue recapitulates the human phenotype.

Journal: Human genomics

Published: November 01, 2024

Damage-Free Shortening of Telomeres Is a Potential Strategy Supporting Blind Mole-Rat Longevity.

Damage-Free Shortening of Telomeres Is a Potential Strategy Supporting Blind Mole-Rat Longevity.

Journal: Genes

Published: February 16, 2023

Senescent Secretome of Blind Mole Rat Spalax Inhibits Malignant Behavior of Human Breast Cancer Cells Triggering Bystander Senescence and Targeting Inflammatory Response.

Senescent Secretome of Blind Mole Rat Spalax Inhibits Malignant Behavior of Human Breast Cancer Cells Triggering Bystander Senescence and Targeting Inflammatory Response.

Journal: International journal of molecular sciences

Published: February 07, 2023

Aging without inflammaging: lesson from Spalax.

Aging without inflammaging: lesson from Spalax.

Journal: Aging

Published: July 28, 2020

Telomeres and Longevity: A Cause or an Effect?

Telomeres and Longevity: A Cause or an Effect?

Journal: International journal of molecular sciences

Published: May 02, 2019

Downregulation of the inflammatory network in senescent fibroblasts and aging tissues of the long-lived and cancer-resistant subterranean wild rodent, Spalax.

Downregulation of the inflammatory network in senescent fibroblasts and aging tissues of the long-lived and cancer-resistant subterranean wild rodent, Spalax.

Journal: Aging cell

Published: April 10, 2019

The transcriptome landscape of the carcinogenic treatment response in the blind mole rat: insights into cancer resistance mechanisms.

The transcriptome landscape of the carcinogenic treatment response in the blind mole rat: insights into cancer resistance mechanisms.

Journal: BMC genomics

Published: September 12, 2018

Adipose-Derived Stem Cells of Blind Mole Rat Spalax Exhibit Reduced Homing Ability: Molecular Mechanisms and Potential Role in Cancer Suppression.

Adipose-Derived Stem Cells of Blind Mole Rat Spalax Exhibit Reduced Homing Ability: Molecular Mechanisms and Potential Role in Cancer Suppression.

Journal: Stem cells (Dayton, Ohio)

Published: March 03, 2018

Adaptive patterns in the p53 protein sequence of the hypoxia- and cancer-tolerant blind mole rat Spalax.

Adaptive patterns in the p53 protein sequence of the hypoxia- and cancer-tolerant blind mole rat Spalax.

Journal: BMC evolutionary biology

Published: November 18, 2015

Iron-rich ferritin in the hypoxia-tolerant rodent Spalax ehrenbergi: a naturally-occurring biomarker confirms the internalization and pathways of intracellular macromolecules.

Iron-rich ferritin in the hypoxia-tolerant rodent Spalax ehrenbergi: a naturally-occurring biomarker confirms the internalization and pathways of intracellular macromolecules.

Journal: Journal of structural biology

Published: March 07, 2014

What's in a name?-"Lipolysosome": ultrastructural features of a lipid-containing organelle.

What's in a name?-"Lipolysosome": ultrastructural features of a lipid-containing organelle.

Journal: Ultrastructural pathology

Published: September 20, 2013

Pronounced cancer resistance in a subterranean rodent, the blind mole-rat, Spalax: in vivo and in vitro evidence.

Pronounced cancer resistance in a subterranean rodent, the blind mole-rat, Spalax: in vivo and in vitro evidence.

Journal: BMC biology

Published: April 18, 2013

Showing 1-12 of 16

Last Updated: 09/26/2026