Irene Hallyburton

Dow Street
Dundee, SCT, United Kingdom

Last Updated: 09/26/2026

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Found 28 publications

ResMAP-a saturation mutagenesis platform enabling parallel profiling of target-specific resistance-conferring mutations in Plasmodium.

ResMAP-a saturation mutagenesis platform enabling parallel profiling of target-specific resistance-conferring mutations in Plasmodium.

Journal: mBio

Published: August 27, 2024

Development of a 2,4-Diaminothiazole Series for the Treatment of Human African Trypanosomiasis Highlights the Importance of Static-Cidal Screening of Analogues.

Development of a 2,4-Diaminothiazole Series for the Treatment of Human African Trypanosomiasis Highlights the Importance of Static-Cidal Screening of Analogues.

Journal: Journal of medicinal chemistry

Published: June 21, 2023

Toolkit of Approaches To Support Target-Focused Drug Discovery for Plasmodium falciparum Lysyl tRNA Synthetase.

Toolkit of Approaches To Support Target-Focused Drug Discovery for Plasmodium falciparum Lysyl tRNA Synthetase.

Journal: ACS infectious diseases

Published: August 29, 2022

Exploring a Tetrahydroquinoline Antimalarial Hit from the Medicines for Malaria Pathogen Box and Identification of its Mode of Resistance as PfeEF2.

Exploring a Tetrahydroquinoline Antimalarial Hit from the Medicines for Malaria Pathogen Box and Identification of its Mode of Resistance as PfeEF2.

Journal: ChemMedChem

Published: July 18, 2022

Preparation, biological evaluation and QSAR analysis of urea substituted 2,4-diamino-pyrimidine anti-malarials.

Preparation, biological evaluation and QSAR analysis of urea substituted 2,4-diamino-pyrimidine anti-malarials.

Journal: RSC medicinal chemistry

Published: July 10, 2022

An Open Drug Discovery Competition: Experimental Validation of Predictive Models in a Series of Novel Antimalarials.

An Open Drug Discovery Competition: Experimental Validation of Predictive Models in a Series of Novel Antimalarials.

Journal: Journal of medicinal chemistry

Published: November 08, 2021

Preparation, biological & cheminformatics-based assessment of N2,N4-diphenylpyrimidine-2,4-diamine as potential Kinase-targeted antimalarials.

Preparation, biological & cheminformatics-based assessment of N2,N4-diphenylpyrimidine-2,4-diamine as potential Kinase-targeted antimalarials.

Journal: Bioorganic & medicinal chemistry

Published: May 06, 2021

Potent antiplasmodial alkaloids from the rhizobacterium Pantoea agglomerans as hemozoin modulators.

Potent antiplasmodial alkaloids from the rhizobacterium Pantoea agglomerans as hemozoin modulators.

Journal: Bioorganic chemistry

Published: January 25, 2021

Escaping from Flatland: Antimalarial Activity of sp3-Rich Bridged Pyrrolidine Derivatives.

Escaping from Flatland: Antimalarial Activity of sp3-Rich Bridged Pyrrolidine Derivatives.

Journal: ACS medicinal chemistry letters

Published: September 04, 2020

Nonclassical Phenyl Bioisosteres as Effective Replacements in a Series of Novel Open-Source Antimalarials.

Nonclassical Phenyl Bioisosteres as Effective Replacements in a Series of Novel Open-Source Antimalarials.

Journal: Journal of medicinal chemistry

Published: July 18, 2020

Substituted Aminoacetamides as Novel Leads for Malaria Treatment.

Substituted Aminoacetamides as Novel Leads for Malaria Treatment.

Journal: ChemMedChem

Published: June 01, 2019

Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis.

Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: March 22, 2019

Showing 1-12 of 28

Last Updated: 09/26/2026