Irene Knuesel

Basel, BS 4070, Switzerland

Last Updated: 09/26/2026

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Found 29 publications

Selective GPR17 antagonism enhances structural and functional recovery in animal models of demyelination.

Selective GPR17 antagonism enhances structural and functional recovery in animal models of demyelination.

Journal: PloS one
Published: March 16, 2026

Differential Expression of Serum Extracellular Vesicle miRNAs in Multiple Sclerosis: Disease-Stage Specificity and Relevance to Pathophysiology.

Differential Expression of Serum Extracellular Vesicle miRNAs in Multiple Sclerosis: Disease-Stage Specificity and Relevance to Pathophysiology.

Journal: International journal of molecular sciences
Published: January 04, 2022

Evidence for Effects of Extracellular Vesicles on Physical, Inflammatory, Transcriptome and Reward Behaviour Status in Mice.

Evidence for Effects of Extracellular Vesicles on Physical, Inflammatory, Transcriptome and Reward Behaviour Status in Mice.

Journal: International journal of molecular sciences
Published: October 15, 2021

Identification and Preclinical Development of a 2,5,6-Trisubstituted Fluorinated Pyridine Derivative as a Radioligand for the Positron Emission Tomography Imaging of Cannabinoid Type 2 Receptors.

Identification and Preclinical Development of a 2,5,6-Trisubstituted Fluorinated Pyridine Derivative as a Radioligand for the Positron Emission Tomography Imaging of Cannabinoid Type 2 Receptors.

Journal: Journal of medicinal chemistry
Published: August 14, 2020

Structure-Activity Relationship Studies of Pyridine-Based Ligands and Identification of a Fluorinated Derivative for Positron Emission Tomography Imaging of Cannabinoid Type 2 Receptors.

Structure-Activity Relationship Studies of Pyridine-Based Ligands and Identification of a Fluorinated Derivative for Positron Emission Tomography Imaging of Cannabinoid Type 2 Receptors.

Journal: Journal of medicinal chemistry
Published: November 22, 2019

Altered human oligodendrocyte heterogeneity in multiple sclerosis.

Altered human oligodendrocyte heterogeneity in multiple sclerosis.

Journal: Nature
Published: July 17, 2018

Evolution of a maternal immune activation (mIA) model in rats: Early developmental effects.

Evolution of a maternal immune activation (mIA) model in rats: Early developmental effects.

Journal: Brain, behavior, and immunity
Published: June 15, 2018

An In Vitro Bone Model to Investigate the Role of Triggering Receptor Expressed on Myeloid Cells-2 in Bone Homeostasis.

An In Vitro Bone Model to Investigate the Role of Triggering Receptor Expressed on Myeloid Cells-2 in Bone Homeostasis.

Journal: Tissue engineering. Part C, Methods
Published: June 14, 2018

Contribution of early Alzheimer's disease-related pathophysiology to the development of acquired epilepsy.

Contribution of early Alzheimer's disease-related pathophysiology to the development of acquired epilepsy.

Journal: The European journal of neuroscience
Published: January 21, 2018

NF-κB activation in astrocytes drives a stage-specific beneficial neuroimmunological response in ALS.

NF-κB activation in astrocytes drives a stage-specific beneficial neuroimmunological response in ALS.

Journal: The EMBO journal
Published: November 22, 2017

The FTD-like syndrome causing TREM2 T66M mutation impairs microglia function, brain perfusion, and glucose metabolism.

The FTD-like syndrome causing TREM2 T66M mutation impairs microglia function, brain perfusion, and glucose metabolism.

Journal: The EMBO journal
Published: January 12, 2017

TREM2 deficiency reduces the efficacy of immunotherapeutic amyloid clearance.

TREM2 deficiency reduces the efficacy of immunotherapeutic amyloid clearance.

Journal: EMBO molecular medicine
Published: July 13, 2016
Showing 1-12 of 29

Last Updated: 09/26/2026