Irfan Koca

Yozgat, 66900, Turkey

Last Updated: 09/26/2026

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Found 46 publications

Anticancer and Immunomodulatory Effects of a Thiazolyl Benzodiazepine Targeting HSP90 in ER+ Breast Cancer.

Anticancer and Immunomodulatory Effects of a Thiazolyl Benzodiazepine Targeting HSP90 in ER+ Breast Cancer.

Journal: Pharmaceuticals (Basel, Switzerland)

Published: September 08, 2025

Investigation of Anticancer Properties of Newly Synthesized Pyridazine-Based Inhibitors in Mouse and Human Breast Cancer Cell Line.

Investigation of Anticancer Properties of Newly Synthesized Pyridazine-Based Inhibitors in Mouse and Human Breast Cancer Cell Line.

Journal: Biology

Published: July 10, 2025

Novel Benzimidazole-Urea Phenylalanine Hybrids as Dual-Acting Antimicrobial and Anticancer Agents: In Silico and Biological Evaluation.

Novel Benzimidazole-Urea Phenylalanine Hybrids as Dual-Acting Antimicrobial and Anticancer Agents: In Silico and Biological Evaluation.

Journal: Chemical biology & drug design

Published: April 24, 2025

HSP Inhibitor Sensitize Resistant MCF-7 Cells to Doxorubicin through Suppressing HSP90AB4P Pseudogene and HSPB1 Expression.

HSP Inhibitor Sensitize Resistant MCF-7 Cells to Doxorubicin through Suppressing HSP90AB4P Pseudogene and HSPB1 Expression.

Journal: Anti-cancer agents in medicinal chemistry

Published: December 31, 2024

HSP Inhibitor Sensitize Resistant MCF-7 Cells to Doxorubicin through Suppressing HSP90AB4P Pseudogene and HSPB1 Expression.

HSP Inhibitor Sensitize Resistant MCF-7 Cells to Doxorubicin through Suppressing HSP90AB4P Pseudogene and HSPB1 Expression.

Journal: Anti-cancer agents in medicinal chemistry

Published: December 31, 2024

Design, Synthesis, and Evaluation of Benzimidazole-Carbazole Hybrids Targeting Heat Shock Proteins-Mediated Apoptosis in Breast and Colon Cancer Cells.

Design, Synthesis, and Evaluation of Benzimidazole-Carbazole Hybrids Targeting Heat Shock Proteins-Mediated Apoptosis in Breast and Colon Cancer Cells.

Journal: Drug development research

Published: November 30, 2024

Correction to: Synthesis of novel carbazole hydrazine‑carbothioamide scaffold as potent antioxidant, anticancer and antimicrobial agents.

Correction to: Synthesis of novel carbazole hydrazine‑carbothioamide scaffold as potent antioxidant, anticancer and antimicrobial agents.

Journal: BMC chemistry

Published: September 16, 2024

Synthesis of novel carbazole hydrazine-carbothioamide scaffold as potent antioxidant, anticancer and antimicrobial agents.

Synthesis of novel carbazole hydrazine-carbothioamide scaffold as potent antioxidant, anticancer and antimicrobial agents.

Journal: BMC chemistry

Published: January 18, 2024

Hsp Inhibitor is Affective Against Adenocarcinomic Human Alveolar Basal Epithelial Cells Through Modulating ERK/MAPK Signaling Pathway.

Hsp Inhibitor is Affective Against Adenocarcinomic Human Alveolar Basal Epithelial Cells Through Modulating ERK/MAPK Signaling Pathway.

Journal: Chemistry & biodiversity

Published: November 15, 2023

Synthesis and biological studies of pyrimidine derivatives targeting metabolic enzymes.

Synthesis and biological studies of pyrimidine derivatives targeting metabolic enzymes.

Journal: Archiv der Pharmazie

Published: November 06, 2023

Triad pyrazole-thiazole-coumarin heterocyclic core effectively inhibit HSP and drive cancer cells to apoptosis.

Triad pyrazole-thiazole-coumarin heterocyclic core effectively inhibit HSP and drive cancer cells to apoptosis.

Journal: Journal of biomolecular structure & dynamics

Published: February 24, 2023

Deciphering the Biophysical Properties of Ion Channel Gating Pores by Coumarin-Benzodiazepine Hybrid Derivatives: Selective AMPA Receptor Antagonists.

Deciphering the Biophysical Properties of Ion Channel Gating Pores by Coumarin-Benzodiazepine Hybrid Derivatives: Selective AMPA Receptor Antagonists.

Journal: Molecular neurobiology

Published: February 02, 2023

Showing 1-12 of 46

Last Updated: 09/26/2026