Iris Z. Jaffe

Cardiology

750 Washington St
Boston, MA 02111

Last Updated: 09/26/2026

Save publications for later

Sign Up

Not sure about your diagnosis?

Check Your Symptoms

Found 113 publications

Mechanisms for Mineralocorticoid-Driven Age-Related Hypertension: Potential Therapeutic Role of Mineralocorticoid Receptor Antagonists and Aldosterone Synthase Inhibitors.

Mechanisms for Mineralocorticoid-Driven Age-Related Hypertension: Potential Therapeutic Role of Mineralocorticoid Receptor Antagonists and Aldosterone Synthase Inhibitors.

Journal: Circulation research

Published: July 16, 2026

Endothelial Estrogen Receptor Alpha Inhibits Plaque Inflammation in Both Sexes.

Endothelial Estrogen Receptor Alpha Inhibits Plaque Inflammation in Both Sexes.

Journal: Circulation research

Published: June 10, 2026

Carvedilol Exerts Cardioprotective Effects Against Doxorubicin Toxicity via Autophagy Modulation and Energetics Restoration.

Carvedilol Exerts Cardioprotective Effects Against Doxorubicin Toxicity via Autophagy Modulation and Energetics Restoration.

Journal: Pharmaceuticals (Basel, Switzerland)

Published: April 20, 2026

Response by Stepanian and Jaffe to Letters Regarding Article, "Ponatinib, but Not the New Abl-Kinase Inhibitor Asciminib, Activates Platelets, Leukocytes, and Endothelial Cell TNF Signaling to Induce Atherosclerotic Plaque Inflammation, Myocardial Infarction, and Stroke".

Response by Stepanian and Jaffe to Letters Regarding Article, "Ponatinib, but Not the New Abl-Kinase Inhibitor Asciminib, Activates Platelets, Leukocytes, and Endothelial Cell TNF Signaling to Induce Atherosclerotic Plaque Inflammation, Myocardial Infarction, and Stroke".

Journal: Circulation

Published: April 06, 2026

Smooth muscle cell estrogen receptor alpha promotes arterial stiffness in the absence of estradiol.

Smooth muscle cell estrogen receptor alpha promotes arterial stiffness in the absence of estradiol.

Journal: bioRxiv : the preprint server for biology

Published: March 18, 2026

Emerging roles for endothelial mineralocorticoid receptor in disease pathogenesis: potential new indications for mineralocorticoid receptor antagonism.

Emerging roles for endothelial mineralocorticoid receptor in disease pathogenesis: potential new indications for mineralocorticoid receptor antagonism.

Journal: Current opinion in physiology

Published: March 11, 2026

Coronary Atherosclerosis in Patients With Cancer and Survivors: A Scientific Statement From the American Heart Association.

Coronary Atherosclerosis in Patients With Cancer and Survivors: A Scientific Statement From the American Heart Association.

Journal: Circulation

Published: February 09, 2026

Ponatinib, But Not the New Abl-Kinase Inhibitor Asciminib, Activates Platelets, Leukocytes, and Endothelial Cell TNF Signaling to Induce Atherosclerotic Plaque Inflammation, Myocardial Infarction, and Stroke.

Ponatinib, But Not the New Abl-Kinase Inhibitor Asciminib, Activates Platelets, Leukocytes, and Endothelial Cell TNF Signaling to Induce Atherosclerotic Plaque Inflammation, Myocardial Infarction, and Stroke.

Journal: Circulation

Published: August 05, 2025

Distinct endothelial cell toxicities of Abl tyrosine kinase inhibitors lead to arterial thrombosis.

Distinct endothelial cell toxicities of Abl tyrosine kinase inhibitors lead to arterial thrombosis.

Journal: Blood vessels, thrombosis & hemostasis

Published: July 08, 2025

The angiotensin II type 2 receptor attenuates aging-associated arterial stiffness in female mice.

The angiotensin II type 2 receptor attenuates aging-associated arterial stiffness in female mice.

Journal: American journal of physiology. Heart and circulatory physiology

Published: July 07, 2025

Rapamycin reduces mineral density and promotes beneficial vascular remodeling in a murine model of severe medial arterial calcification.

Rapamycin reduces mineral density and promotes beneficial vascular remodeling in a murine model of severe medial arterial calcification.

Journal: American journal of physiology. Heart and circulatory physiology

Published: May 08, 2025

Microvascular angiotensin II type 2 receptor function is enhanced in young females and declines in a model of murine aging.

Microvascular angiotensin II type 2 receptor function is enhanced in young females and declines in a model of murine aging.

Journal: The journal of cardiovascular aging

Published: April 28, 2025

Showing 1-12 of 113

Last Updated: 09/26/2026