Irma Martinez-Garcia

Madrid, MD 28029, Spain

Last Updated: 09/26/2026

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Found 23 publications

Deletion of Pleiotrophin protects against high-fat diet-induced liver metabolic disease, independently of the sexual dimorphism in dietary response.

Deletion of Pleiotrophin protects against high-fat diet-induced liver metabolic disease, independently of the sexual dimorphism in dietary response.

Journal: Molecular biomedicine
Published: August 27, 2025

Effect of lipotoxic hepatocyte-derived extracellular vesicles in pancreas inflammation: essential role of macrophage TLR4 in beta cell functionality.

Effect of lipotoxic hepatocyte-derived extracellular vesicles in pancreas inflammation: essential role of macrophage TLR4 in beta cell functionality.

Journal: Diabetologia
Published: January 07, 2025

Specific targeting of the NRF2/β-TrCP axis promotes beneficial effects in NASH.

Specific targeting of the NRF2/β-TrCP axis promotes beneficial effects in NASH.

Journal: Redox biology
Published: November 17, 2023

Hypothalamic JNK1-hepatic fatty acid synthase axis mediates a metabolic rewiring that prevents hepatic steatosis in male mice treated with olanzapine via intraperitoneal: Additional effects of PTP1B inhibition.

Hypothalamic JNK1-hepatic fatty acid synthase axis mediates a metabolic rewiring that prevents hepatic steatosis in male mice treated with olanzapine via intraperitoneal: Additional effects of PTP1B inhibition.

Journal: Redox biology
Published: April 21, 2023

Saturated fatty acid-enriched small extracellular vesicles mediate a crosstalk inducing liver inflammation and hepatocyte insulin resistance.

Saturated fatty acid-enriched small extracellular vesicles mediate a crosstalk inducing liver inflammation and hepatocyte insulin resistance.

Journal: JHEP reports : innovation in hepatology
Published: July 07, 2022

Metformin reduces macrophage HIF1α-dependent proinflammatory signaling to restore brown adipocyte function in vitro.

Metformin reduces macrophage HIF1α-dependent proinflammatory signaling to restore brown adipocyte function in vitro.

Journal: Redox biology
Published: September 20, 2021

The dual GLP-1/glucagon receptor agonist G49 mimics bariatric surgery effects by inducing metabolic rewiring and inter-organ crosstalk.

The dual GLP-1/glucagon receptor agonist G49 mimics bariatric surgery effects by inducing metabolic rewiring and inter-organ crosstalk.

Journal: Nature communications
Published: April 07, 2021

Insights Into Extracellular Vesicles as Biomarker of NAFLD Pathogenesis.

Insights Into Extracellular Vesicles as Biomarker of NAFLD Pathogenesis.

Journal: Frontiers in medicine
Published: April 27, 2020

Impact of global PTP1B deficiency on the gut barrier permeability during NASH in mice.

Impact of global PTP1B deficiency on the gut barrier permeability during NASH in mice.

Journal: Molecular metabolism
Published: October 21, 2019

Impact of Bacterial Translocation on Sarcopenia in Patients with Decompensated Cirrhosis.

Impact of Bacterial Translocation on Sarcopenia in Patients with Decompensated Cirrhosis.

Journal: Nutrients
Published: August 20, 2019

Ammonia-Induced Brain Edema Requires Macrophage and T Cell Expression of Toll-Like Receptor 9.

Ammonia-Induced Brain Edema Requires Macrophage and T Cell Expression of Toll-Like Receptor 9.

Journal: Cellular and molecular gastroenterology and hepatology
Published: May 22, 2019

Digoxin Suppresses Pyruvate Kinase M2-Promoted HIF-1α Transactivation in Steatohepatitis.

Digoxin Suppresses Pyruvate Kinase M2-Promoted HIF-1α Transactivation in Steatohepatitis.

Journal: Cell metabolism
Published: May 03, 2018
Showing 1-12 of 23

Last Updated: 09/26/2026