Irma Tindemans

Rotterdam, ZH, Netherlands

Last Updated: 09/26/2026

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Found 13 publications

Gut-homing and intestinal TIGITnegCD38+ memory T cells acquire an IL-12-induced, ex-Th17 pathogenic phenotype in a subgroup of Crohn's disease patients with a severe disease course.

Gut-homing and intestinal TIGITnegCD38+ memory T cells acquire an IL-12-induced, ex-Th17 pathogenic phenotype in a subgroup of Crohn's disease patients with a severe disease course.

Journal: Mucosal immunology

Published: June 01, 2024

Serum Immune Profiling in Paediatric Crohn's Disease Demonstrates Stronger Immune Modulation With First-Line Infliximab Than Conventional Therapy and Pre-Treatment Profiles Predict Clinical Response to Both Treatments.

Serum Immune Profiling in Paediatric Crohn's Disease Demonstrates Stronger Immune Modulation With First-Line Infliximab Than Conventional Therapy and Pre-Treatment Profiles Predict Clinical Response to Both Treatments.

Journal: Journal of Crohn's & colitis

Published: March 19, 2023

International prospective observational study investigating the disease course and heterogeneity of paediatric-onset inflammatory bowel disease: the protocol of the PIBD-SETQuality inception cohort study.

International prospective observational study investigating the disease course and heterogeneity of paediatric-onset inflammatory bowel disease: the protocol of the PIBD-SETQuality inception cohort study.

Journal: BMJ open

Published: July 03, 2020

Dissecting the Heterogeneity in T-Cell Mediated Inflammation in IBD.

Dissecting the Heterogeneity in T-Cell Mediated Inflammation in IBD.

Journal: Cells

Published: October 30, 2019

Type II conventional dendritic cells of asthmatic patients with frequent exacerbations have an altered phenotype and frequency.

Type II conventional dendritic cells of asthmatic patients with frequent exacerbations have an altered phenotype and frequency.

Journal: The European respiratory journal

Published: April 26, 2019

Notch signaling licenses allergic airway inflammation by promoting Th2 cell lymph node egress.

Notch signaling licenses allergic airway inflammation by promoting Th2 cell lymph node egress.

Journal: The Journal of clinical investigation

Published: February 20, 2019

Increased surface expression of NOTCH on memory T cells in peripheral blood from patients with asthma.

Increased surface expression of NOTCH on memory T cells in peripheral blood from patients with asthma.

Journal: The Journal of allergy and clinical immunology

Published: July 01, 2018

Frequencies of circulating regulatory TIGIT+CD38+ effector T cells correlate with the course of inflammatory bowel disease.

Frequencies of circulating regulatory TIGIT+CD38+ effector T cells correlate with the course of inflammatory bowel disease.

Journal: Mucosal immunology

Published: March 14, 2018

Notch Signaling in T Helper Cell Subsets: Instructor or Unbiased Amplifier?

Notch Signaling in T Helper Cell Subsets: Instructor or Unbiased Amplifier?

Journal: Frontiers in immunology

Published: January 23, 2017

The Notch pathway inhibitor stapled α-helical peptide derived from mastermind-like 1 (SAHM1) abrogates the hallmarks of allergic asthma.

The Notch pathway inhibitor stapled α-helical peptide derived from mastermind-like 1 (SAHM1) abrogates the hallmarks of allergic asthma.

Journal: The Journal of allergy and clinical immunology

Published: November 19, 2016

Notch signaling in T cells is essential for allergic airway inflammation, but expression of the Notch ligands Jagged 1 and Jagged 2 on dendritic cells is dispensable.

Notch signaling in T cells is essential for allergic airway inflammation, but expression of the Notch ligands Jagged 1 and Jagged 2 on dendritic cells is dispensable.

Journal: The Journal of allergy and clinical immunology

Published: June 16, 2016

T cells are necessary for ILC2 activation in house dust mite-induced allergic airway inflammation in mice.

T cells are necessary for ILC2 activation in house dust mite-induced allergic airway inflammation in mice.

Journal: European journal of immunology

Published: October 12, 2015

Showing 1-12 of 13

Last Updated: 09/26/2026