Isabella Barbiero

Busto Arsizio, Italy

Last Updated: 09/26/2026

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Found 16 publications

CDKL5 regulates the initiation of retrograde axonal transport through CLIP170-dynactin complex formation.

CDKL5 regulates the initiation of retrograde axonal transport through CLIP170-dynactin complex formation.

Journal: The FEBS journal

Published: September 22, 2024

Loss of CDKL5 Causes Synaptic GABAergic Defects That Can Be Restored with the Neuroactive Steroid Pregnenolone-Methyl-Ether.

Loss of CDKL5 Causes Synaptic GABAergic Defects That Can Be Restored with the Neuroactive Steroid Pregnenolone-Methyl-Ether.

Journal: International journal of molecular sciences

Published: November 02, 2022

Pregnenolone-methyl-ether enhances CLIP170 and microtubule functions improving spine maturation and hippocampal deficits related to CDKL5 deficiency.

Pregnenolone-methyl-ether enhances CLIP170 and microtubule functions improving spine maturation and hippocampal deficits related to CDKL5 deficiency.

Journal: Human molecular genetics

Published: October 29, 2021

Therapeutic potential of pregnenolone and pregnenolone methyl ether on depressive and CDKL5 deficiency disorders: Focus on microtubule targeting.

Therapeutic potential of pregnenolone and pregnenolone methyl ether on depressive and CDKL5 deficiency disorders: Focus on microtubule targeting.

Journal: Journal of neuroendocrinology

Published: June 06, 2021

Author Correction: Brain phosphorylation of MeCP2 at serine 164 is developmentally regulated and globally alters its chromatin association.

Author Correction: Brain phosphorylation of MeCP2 at serine 164 is developmentally regulated and globally alters its chromatin association.

Journal: Scientific reports

Published: May 27, 2021

The green tea polyphenol epigallocatechin-3-gallate (EGCG) restores CDKL5-dependent synaptic defects in vitro and in vivo.

The green tea polyphenol epigallocatechin-3-gallate (EGCG) restores CDKL5-dependent synaptic defects in vitro and in vivo.

Journal: Neurobiology of disease

Published: August 27, 2019

Microtubules: A Key to Understand and Correct Neuronal Defects in CDKL5 Deficiency Disorder?

Microtubules: A Key to Understand and Correct Neuronal Defects in CDKL5 Deficiency Disorder?

Journal: International journal of molecular sciences

Published: July 25, 2019

Pregnenolone and pregnenolone-methyl-ether rescue neuronal defects caused by dysfunctional CLIP170 in a neuronal model of CDKL5 Deficiency Disorder.

Pregnenolone and pregnenolone-methyl-ether rescue neuronal defects caused by dysfunctional CLIP170 in a neuronal model of CDKL5 Deficiency Disorder.

Journal: Neuropharmacology

Published: June 20, 2019

Cannabidivarin completely rescues cognitive deficits and delays neurological and motor defects in male Mecp2 mutant mice.

Cannabidivarin completely rescues cognitive deficits and delays neurological and motor defects in male Mecp2 mutant mice.

Journal: Journal of psychopharmacology (Oxford, England)

Published: May 16, 2019

The antidepressant tianeptine reverts synaptic AMPA receptor defects caused by deficiency of CDKL5.

The antidepressant tianeptine reverts synaptic AMPA receptor defects caused by deficiency of CDKL5.

Journal: Human molecular genetics

Published: February 21, 2018

The neurosteroid pregnenolone reverts microtubule derangement induced by the loss of a functional CDKL5-IQGAP1 complex.

The neurosteroid pregnenolone reverts microtubule derangement induced by the loss of a functional CDKL5-IQGAP1 complex.

Journal: Human molecular genetics

Published: March 31, 2017

CDKL5 localizes at the centrosome and midbody and is required for faithful cell division.

CDKL5 localizes at the centrosome and midbody and is required for faithful cell division.

Journal: Scientific reports

Published: January 25, 2017

Showing 1-12 of 16

Last Updated: 09/26/2026