Isabella Tessari

Padova, Italy

Last Updated: 09/26/2026

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Found 27 publications

PAK6 rescues pathogenic LRRK2-mediated ciliogenesis and centrosomal cohesion defects in a mutation-specific manner.

PAK6 rescues pathogenic LRRK2-mediated ciliogenesis and centrosomal cohesion defects in a mutation-specific manner.

Journal: Cell death & disease

Published: April 13, 2024

Developing nanobodies as allosteric molecular chaperones of glucocerebrosidase function.

Developing nanobodies as allosteric molecular chaperones of glucocerebrosidase function.

Journal: Nature communications

Published: March 26, 2024

Copper Binding and Redox Activity of α-Synuclein in Membrane-Like Environment.

Copper Binding and Redox Activity of α-Synuclein in Membrane-Like Environment.

Journal: Biomolecules

Published: December 31, 2022

Cytosolic sequestration of spatacsin by Protein Kinase A and 14-3-3 proteins.

Cytosolic sequestration of spatacsin by Protein Kinase A and 14-3-3 proteins.

Journal: Neurobiology of disease

Published: May 23, 2022

The Roc domain of LRRK2 as a hub for protein-protein interactions: a focus on PAK6 and its impact on RAB phosphorylation.

The Roc domain of LRRK2 as a hub for protein-protein interactions: a focus on PAK6 and its impact on RAB phosphorylation.

Journal: Brain research

Published: May 28, 2021

Parkinson's Disease-Associated LRRK2 Interferes with Astrocyte-Mediated Alpha-Synuclein Clearance.

Parkinson's Disease-Associated LRRK2 Interferes with Astrocyte-Mediated Alpha-Synuclein Clearance.

Journal: Molecular neurobiology

Published: October 30, 2020

Extracellular clusterin limits the uptake of α-synuclein fibrils by murine and human astrocytes.

Extracellular clusterin limits the uptake of α-synuclein fibrils by murine and human astrocytes.

Journal: Glia

Published: June 12, 2020

Fibrils of α-Synuclein Abolish the Affinity of Cu2+-Binding Site to His50 and Induce Hopping of Cu2+ Ions in the Termini.

Fibrils of α-Synuclein Abolish the Affinity of Cu2+-Binding Site to His50 and Induce Hopping of Cu2+ Ions in the Termini.

Journal: Inorganic chemistry

Published: August 02, 2019

Determination of ATP, ADP, and AMP Levels by Reversed-Phase High-Performance Liquid Chromatography in Cultured Cells.

Determination of ATP, ADP, and AMP Levels by Reversed-Phase High-Performance Liquid Chromatography in Cultured Cells.

Journal: Methods in molecular biology (Clifton, N.J.)

Published: January 24, 2019

Transcriptome analysis of LRRK2 knock-out microglia cells reveals alterations of inflammatory- and oxidative stress-related pathways upon treatment with α-synuclein fibrils.

Transcriptome analysis of LRRK2 knock-out microglia cells reveals alterations of inflammatory- and oxidative stress-related pathways upon treatment with α-synuclein fibrils.

Journal: Neurobiology of disease

Published: December 06, 2018

PAK6 Phosphorylates 14-3-3γ to Regulate Steady State Phosphorylation of LRRK2.

PAK6 Phosphorylates 14-3-3γ to Regulate Steady State Phosphorylation of LRRK2.

Journal: Frontiers in molecular neuroscience

Published: November 03, 2017

α-Synuclein Dimers Impair Vesicle Fission during Clathrin-Mediated Synaptic Vesicle Recycling.

α-Synuclein Dimers Impair Vesicle Fission during Clathrin-Mediated Synaptic Vesicle Recycling.

Journal: Frontiers in cellular neuroscience

Published: September 22, 2017

Showing 1-12 of 27

Last Updated: 09/26/2026