Isamu Shiina
Tokyo, Japan
Last Updated: 09/26/2026
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Found 44 publications
Syntheses and biological evaluation of M-COPA analogs derived from pentadienoic Weinreb amide.
Journal: Proceedings of the Japan Academy. Series B, Physical and biological sciences
Published: July 21, 2025
Design and Synthesis of Potent Ridaifen Analogues: Evaluation as Anticancer, 20S Proteasomal Inhibitors, and Antiebola Virus Agents through In vitro and In Silico Studies.
Journal: ChemMedChem
Published: June 03, 2025
Ridaifen derivatives function as potent lysosomotropic agents, depending on their basic side chains.
Ridaifen derivatives function as potent lysosomotropic agents, depending on their basic side chains.
Journal: European journal of pharmacology
Published: April 30, 2025
Golgi retention of KIT in gastrointestinal stromal tumour cells is phospholipase D activity-dependent.
Journal: Scientific reports
Published: March 03, 2025
Synthesis of BODIPY FL-tethered ridaifen-B, RID-B-BODIPY, and its localization in cancer cells.
Journal: Frontiers in chemistry
Published: June 19, 2024
Total Synthesis of the Sesquiterpene (-)-Merrillianin.
Journal: Organic letters
Published: December 31, 2023
Brefeldin A and M-COPA block the export of RTKs from the endoplasmic reticulum via simultaneous inactivation of ARF1, ARF4, and ARF5.
Journal: The Journal of biological chemistry
Published: October 17, 2023
BRAP2 inhibits the Ras/Raf/MEK and PI3K/Akt pathways in leukemia cells, thereby inducing apoptosis and inhibiting cell growth.
Journal: Experimental and therapeutic medicine
Published: May 26, 2020
Total Synthesis and Antimicrobial Evaluation of 23-Demethyleushearilide and Extensive Antimicrobial Evaluation of All Synthetic Stereoisomers of (16Z,20E)-Eushearilide and (16E,20E)-Eushearilide.
Journal: Molecules (Basel, Switzerland)
Published: August 07, 2019
N822K- or V560G-mutated KIT activation preferentially occurs in lipid rafts of the Golgi apparatus in leukemia cells.
Journal: Cell communication and signaling : CCS
Published: March 14, 2019
Last Updated: 09/26/2026