Israa A. Seliem

Zagazig, SHR 44511, Egypt

Last Updated: 09/26/2026

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Found 11 publications

Microwave-assisted green synthesis and biological evaluation of a novel isatin-thiazole-benzofuran hybrid with dual acetylcholinesterase inhibitory and antioxidant activities.

Microwave-assisted green synthesis and biological evaluation of a novel isatin-thiazole-benzofuran hybrid with dual acetylcholinesterase inhibitory and antioxidant activities.

Journal: Bioorganic chemistry

Published: April 06, 2026

Microwave-assisted one-pot green synthesis, ADMET profiling, DFT, and molecular docking of novel 3-cyano-2-pyridone derivatives as dual EGFR and cytokine (TNF-α, IL-6) inhibitors.

Microwave-assisted one-pot green synthesis, ADMET profiling, DFT, and molecular docking of novel 3-cyano-2-pyridone derivatives as dual EGFR and cytokine (TNF-α, IL-6) inhibitors.

Journal: European journal of medicinal chemistry

Published: July 30, 2025

Design, eco-friendly synthesis, and molecular docking studies of isatin hybrids as promising therapeutic agents (anticancer, anticholinesterase inhibitor, α-glucosidase inhibitor, and anti-MRSA).

Design, eco-friendly synthesis, and molecular docking studies of isatin hybrids as promising therapeutic agents (anticancer, anticholinesterase inhibitor, α-glucosidase inhibitor, and anti-MRSA).

Journal: RSC advances

Published: July 03, 2025

Synthesis, cytotoxic activity, molecular docking, molecular dynamics simulations, and ADMET studies of novel spiropyrazoline oxindoles based on domino Knoevenagel-Michael cyclization as potent non-toxic anticancer agents targeting β-tubulin and EGFR, with anti-MRSA activity.

Synthesis, cytotoxic activity, molecular docking, molecular dynamics simulations, and ADMET studies of novel spiropyrazoline oxindoles based on domino Knoevenagel-Michael cyclization as potent non-toxic anticancer agents targeting β-tubulin and EGFR, with anti-MRSA activity.

Journal: RSC advances

Published: February 20, 2025

DMF-DMA catalyzed Synthesis, molecular docking, in-vitro, in-silico design, and binding free energy studies of novel thiohydantoin derivatives as antioxidant and antiproliferative agents targeting EGFR tyrosine kinase and aromatase cytochrome P450 enzyme.

DMF-DMA catalyzed Synthesis, molecular docking, in-vitro, in-silico design, and binding free energy studies of novel thiohydantoin derivatives as antioxidant and antiproliferative agents targeting EGFR tyrosine kinase and aromatase cytochrome P450 enzyme.

Journal: Bioorganic chemistry

Published: June 04, 2024

Development of Isatin-Based Schiff Bases Targeting VEGFR-2 Inhibition: Synthesis, Characterization, Antiproliferative Properties, and QSAR Studies.

Development of Isatin-Based Schiff Bases Targeting VEGFR-2 Inhibition: Synthesis, Characterization, Antiproliferative Properties, and QSAR Studies.

Journal: ChemMedChem

Published: March 28, 2022

New Pyrazine Conjugates: Synthesis, Computational Studies, and Antiviral Properties against SARS-CoV-2.

New Pyrazine Conjugates: Synthesis, Computational Studies, and Antiviral Properties against SARS-CoV-2.

Journal: ChemMedChem

Published: July 06, 2021

New quinoline-triazole conjugates: Synthesis, and antiviral properties against SARS-CoV-2.

New quinoline-triazole conjugates: Synthesis, and antiviral properties against SARS-CoV-2.

Journal: Bioorganic chemistry

Published: April 07, 2021

An Efficient Greener Approach for N-Acylation of Amines in Water Using Benzotriazole Chemistry.

An Efficient Greener Approach for N-Acylation of Amines in Water Using Benzotriazole Chemistry.

Journal: Molecules (Basel, Switzerland)

Published: April 28, 2020

In Vitro Antimycobacterial Activity and Physicochemical Characterization of Diaryl Ether Triclosan Analogues as Potential InhA Reductase Inhibitors.

In Vitro Antimycobacterial Activity and Physicochemical Characterization of Diaryl Ether Triclosan Analogues as Potential InhA Reductase Inhibitors.

Journal: Molecules (Basel, Switzerland)

Published: January 28, 2020

Design, synthesis, antimicrobial, and DNA gyrase inhibitory properties of fluoroquinolone-dichloroacetic acid hybrids.

Design, synthesis, antimicrobial, and DNA gyrase inhibitory properties of fluoroquinolone-dichloroacetic acid hybrids.

Journal: Chemical biology & drug design

Published: June 24, 2019

Showing 1-11 of 11

Last Updated: 09/26/2026