Israel Silman

234 Herzl St, 7610001
Rehovot, M 76100, Israel

Last Updated: 09/26/2026

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Found 38 publications

Why is binding of a divalent metal cation to a structural motif containing four carboxylate residues not accompanied by a conformational change?

Why is binding of a divalent metal cation to a structural motif containing four carboxylate residues not accompanied by a conformational change?

Journal: Protein science : a publication of the Protein Society

Published: June 27, 2024

The impact of molecular variants, crystallization conditions and the space group on ligand-protein complexes: a case study on bacterial phosphotriesterase.

The impact of molecular variants, crystallization conditions and the space group on ligand-protein complexes: a case study on bacterial phosphotriesterase.

Journal: Acta crystallographica. Section D, Structural biology

Published: July 18, 2023

Design of a stable human acid-β-glucosidase: towards improved Gaucher disease therapy and mutation classification.

Design of a stable human acid-β-glucosidase: towards improved Gaucher disease therapy and mutation classification.

Journal: The FEBS journal

Published: September 24, 2022

Do "Newly Born" orphan proteins resemble "Never Born" proteins? A study using three deep learning algorithms.

Do "Newly Born" orphan proteins resemble "Never Born" proteins? A study using three deep learning algorithms.

Journal: Proteins

Published: August 02, 2022

Preface: Cholinergic mechanisms: This is the Preface for the special issue "Cholinergic Mechanisms".

Preface: Cholinergic mechanisms: This is the Preface for the special issue "Cholinergic Mechanisms".

Journal: Journal of neurochemistry

Published: July 14, 2021

Discovery of a Potent Dual Inhibitor of Acetylcholinesterase and Butyrylcholinesterase with Antioxidant Activity that Alleviates Alzheimer-like Pathology in Old APP/PS1 Mice.

Discovery of a Potent Dual Inhibitor of Acetylcholinesterase and Butyrylcholinesterase with Antioxidant Activity that Alleviates Alzheimer-like Pathology in Old APP/PS1 Mice.

Journal: Journal of medicinal chemistry

Published: December 28, 2020

Torpedo californica acetylcholinesterase is stabilized by binding of a divalent metal ion to a novel and versatile 4D motif.

Torpedo californica acetylcholinesterase is stabilized by binding of a divalent metal ion to a novel and versatile 4D motif.

Journal: Protein science : a publication of the Protein Society

Published: December 23, 2020

The multiple biological roles of the cholinesterases.

The multiple biological roles of the cholinesterases.

Journal: Progress in biophysics and molecular biology

Published: July 02, 2020

Computational studies on cholinesterases: Strengthening our understanding of the integration of structure, dynamics and function.

Computational studies on cholinesterases: Strengthening our understanding of the integration of structure, dynamics and function.

Journal: Neuropharmacology

Published: April 03, 2020

A Second Look at the Crystal Structures of Drosophila melanogaster Acetylcholinesterase in Complex with Tacrine Derivatives Provides Insights Concerning Catalytic Intermediates and the Design of Specific Insecticides.

A Second Look at the Crystal Structures of Drosophila melanogaster Acetylcholinesterase in Complex with Tacrine Derivatives Provides Insights Concerning Catalytic Intermediates and the Design of Specific Insecticides.

Journal: Molecules (Basel, Switzerland)

Published: February 01, 2020

Chiral Separation, X-ray Structure, and Biological Evaluation of a Potent and Reversible Dual Binding Site AChE Inhibitor.

Chiral Separation, X-ray Structure, and Biological Evaluation of a Potent and Reversible Dual Binding Site AChE Inhibitor.

Journal: ACS medicinal chemistry letters

Published: December 27, 2019

Polyproline-rich peptides associated with Torpedo californica acetylcholinesterase tetramers.

Polyproline-rich peptides associated with Torpedo californica acetylcholinesterase tetramers.

Journal: Chemico-biological interactions

Published: December 25, 2019

Showing 1-12 of 38

Last Updated: 09/26/2026