Italo Poggesi
Janssen R&D
Cologno Monzese, Italy
Cologno Monzese, Italy
Last Updated: 09/26/2026
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Found 45 publications
A Genetic Algorithm-Based Approach for Quantitative Prediction of Drug-Drug Interactions Caused by Cytochrome P450 3A Inhibition or Induction in Horses.
Journal: Pharmaceuticals (Basel, Switzerland)
Published: April 03, 2026
Developing low-carbon metered-dose inhalers: effects of propellant HFA-152a on mucociliary clearance and bronchoconstriction in two Phase 1 randomised trials.
Journal: Respiratory medicine
Published: March 16, 2026
Development of an Empirical Approach for the Prediction of Cytochrome P450-Based Drug-Drug Interactions in Pediatric Patients.
Journal: Pharmaceuticals (Basel, Switzerland)
Published: March 12, 2026
A Randomized Trial on the Combined Effect of Ponesimod and Propranolol on Heart Rate, Cardiac Safety, and Pharmacokinetics in Healthy Adults.
Journal: Clinical and translational science
Published: April 14, 2025
A genetic algorithm-based approach for quantitative prediction of drug-drug interactions caused by cytochrome P450 3A inhibitors and inducers in dogs and cats.
Journal: Chemico-biological interactions
Published: February 28, 2025
Pharmacokinetics of intranasal drugs, still a missed opportunity?
Journal: Xenobiotica; the fate of foreign compounds in biological systems
Published: April 30, 2024
A genetic algorithm-based approach for the prediction of metabolic drug-drug interactions involving CYP2C8 or CYP2B6.
Journal: Journal of pharmacological and toxicological methods
Published: March 29, 2024
Quantitative Prediction of Drug Interactions Caused by Cytochrome P450 2B6 Inhibition or Induction.
Journal: Clinical pharmacokinetics
Published: June 29, 2022
Pharmacokinetic-Pharmacodynamic Modeling of the Ponesimod Effect on Heart Rate in Patients With Multiple Sclerosis.
Journal: Clinical pharmacology and therapeutics
Published: February 18, 2022
A Quantitative Approach to the Prediction of Drug-Drug Interactions Mediated by Cytochrome P450 2C8 Inhibition.
Journal: Expert opinion on drug metabolism & toxicology
Published: November 01, 2021
General clinical and methodological considerations on the extrapolation of pharmacokinetics and optimization of study protocols for small molecules and monoclonal antibodies in children.
Journal: British journal of clinical pharmacology
Published: October 21, 2021
An exposure-response analysis of ponesimod clinical efficacy in a randomized phase III study in patients with relapsing multiple sclerosis.
Journal: CPT: pharmacometrics & systems pharmacology
Published: September 19, 2021
Last Updated: 09/26/2026