Izidor Sosic

Ljubljana, Slovenia

Last Updated: 09/26/2026

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Found 81 publications

Fluorinated Aminopiperidones as Non-Glutarimide Thalidomide Analogs: Stereodivergent Synthesis and Validation.

Fluorinated Aminopiperidones as Non-Glutarimide Thalidomide Analogs: Stereodivergent Synthesis and Validation.

Journal: ChemMedChem
Published: June 02, 2026

α-Aminoboronic Acid Moieties in Boro Dipeptides Modulate Proteasome Subunit Selectivity and Provide Access to Compounds with Potent Anticancer and Anti-Inflammatory Activity.

α-Aminoboronic Acid Moieties in Boro Dipeptides Modulate Proteasome Subunit Selectivity and Provide Access to Compounds with Potent Anticancer and Anti-Inflammatory Activity.

Journal: Journal of medicinal chemistry
Published: December 04, 2025

A Facile Protocol for C(sp2)-C(sp3) Bond Formation Reactions Toward Functionalized E3 Ligase Ligands.

A Facile Protocol for C(sp2)-C(sp3) Bond Formation Reactions Toward Functionalized E3 Ligase Ligands.

Journal: ChemMedChem
Published: October 17, 2025

Synthesis and structure-activity relationship study of novel quinazolin-4(3H)-one derivatives as Toll-like receptor 7 and 8 agonists with immunomodulatory activity.

Synthesis and structure-activity relationship study of novel quinazolin-4(3H)-one derivatives as Toll-like receptor 7 and 8 agonists with immunomodulatory activity.

Journal: European journal of medicinal chemistry
Published: August 14, 2025

Enhancing Solubility in VHL-Based PROTACs: Optimized USP7 Degraders for Improved Developability.

Enhancing Solubility in VHL-Based PROTACs: Optimized USP7 Degraders for Improved Developability.

Journal: Journal of medicinal chemistry
Published: July 17, 2025

Mechanistic insight into the dynamics of Mur ligase through a comprehensive timescale-specific approach.

Mechanistic insight into the dynamics of Mur ligase through a comprehensive timescale-specific approach.

Journal: Communications chemistry
Published: June 03, 2025

Biochemical characteristics of the 6-nitro regioisomer of nitroxoline and its 1,2,3,4-tetrahydroquinoline analogues.

Biochemical characteristics of the 6-nitro regioisomer of nitroxoline and its 1,2,3,4-tetrahydroquinoline analogues.

Journal: Acta pharmaceutica (Zagreb, Croatia)
Published: May 30, 2025

Development and evaluation of novel InhA inhibitors inspired by thiadiazole and tetrahydropyran series of inhibitors.

Development and evaluation of novel InhA inhibitors inspired by thiadiazole and tetrahydropyran series of inhibitors.

Journal: Acta pharmaceutica (Zagreb, Croatia)
Published: May 21, 2025

OSMI-4-based PROTACs do not influence O-GlcNAc transferase and O-GlcNAcylation levels in cells.

OSMI-4-based PROTACs do not influence O-GlcNAc transferase and O-GlcNAcylation levels in cells.

Journal: RSC advances
Published: April 22, 2025

Access to amidines via C(sp2)-N coupling of trifluoroborate-iminiums with N-fluorobenzenesulfonimide.

Access to amidines via C(sp2)-N coupling of trifluoroborate-iminiums with N-fluorobenzenesulfonimide.

Journal: Chemical science
Published: April 21, 2025

Optimization of 6-(trifluoromethyl)pyrimidine derivatives as TLR8 antagonists.

Optimization of 6-(trifluoromethyl)pyrimidine derivatives as TLR8 antagonists.

Journal: Acta pharmaceutica (Zagreb, Croatia)
Published: March 28, 2025

Targeting TAK1: Evolution of inhibitors, challenges, and future directions.

Targeting TAK1: Evolution of inhibitors, challenges, and future directions.

Journal: Pharmacology & therapeutics
Published: November 15, 2024
Showing 1-12 of 81

Last Updated: 09/26/2026