Izzeddin Alsalahat

Cardiff, WLS, United Kingdom

Last Updated: 09/26/2026

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Found 19 publications

Indoles-A Targeting the PI3K/Akt/mTOR Pathway: Recent Advances in Strategic Design, Mechanism, and Future Perspectives.

Indoles-A Targeting the PI3K/Akt/mTOR Pathway: Recent Advances in Strategic Design, Mechanism, and Future Perspectives.

Journal: Archiv der Pharmazie

Published: December 04, 2025

Chitosan/polyacrylic acid nanogel-mediated delivery system for cancer treatment: Design, synthesis, ADMET, docking of thiazole derivatives as dual inhibitors of VEGFR-2 and EGFRT790M.

Chitosan/polyacrylic acid nanogel-mediated delivery system for cancer treatment: Design, synthesis, ADMET, docking of thiazole derivatives as dual inhibitors of VEGFR-2 and EGFRT790M.

Journal: Bioorganic chemistry

Published: August 19, 2025

Ferulic acid mitigates 3-Nitropropionic acid-induced Huntington's disease via modulation of Nrf2/HO-1, TLR4/NF-κB, and SIRT1/p53 signaling pathways.

Ferulic acid mitigates 3-Nitropropionic acid-induced Huntington's disease via modulation of Nrf2/HO-1, TLR4/NF-κB, and SIRT1/p53 signaling pathways.

Journal: Frontiers in pharmacology

Published: August 03, 2025

A literature review on pharmacological aspects, docking studies, and synthetic approaches of quinazoline and quinazolinone derivatives.

A literature review on pharmacological aspects, docking studies, and synthetic approaches of quinazoline and quinazolinone derivatives.

Journal: Archiv der Pharmazie

Published: January 22, 2024

Design and construction of novel pyridine-pyrimidine hybrids as selective COX-2 suppressors: anti-inflammatory potential, ulcerogenic profile, molecular modeling and ADME/Tox studies.

Design and construction of novel pyridine-pyrimidine hybrids as selective COX-2 suppressors: anti-inflammatory potential, ulcerogenic profile, molecular modeling and ADME/Tox studies.

Journal: Journal of biomolecular structure & dynamics

Published: December 28, 2023

Tunable Polymeric Mixed Micellar Nanoassemblies of Lutrol F127/Gelucire 44/14 for Oral Delivery of Praziquantel: A Promising Nanovector against Hymenolepis nana in Experimentally-Infected Rats.

Tunable Polymeric Mixed Micellar Nanoassemblies of Lutrol F127/Gelucire 44/14 for Oral Delivery of Praziquantel: A Promising Nanovector against Hymenolepis nana in Experimentally-Infected Rats.

Journal: Pharmaceutics

Published: August 19, 2022

Bilosomes as a promising nanoplatform for oral delivery of an alkaloid nutraceutical: improved pharmacokinetic profile and snowballed hypoglycemic effect in diabetic rats.

Bilosomes as a promising nanoplatform for oral delivery of an alkaloid nutraceutical: improved pharmacokinetic profile and snowballed hypoglycemic effect in diabetic rats.

Journal: Drug delivery

Published: August 17, 2022

Facile Conversion of the Quinone-Semicarbazone Chromophore of Naftazone into a Fluorescent Quinol-Semicarbazide: Kinetic Study and Analysis of Naftazone in Pharmaceuticals and Human Serum.

Facile Conversion of the Quinone-Semicarbazone Chromophore of Naftazone into a Fluorescent Quinol-Semicarbazide: Kinetic Study and Analysis of Naftazone in Pharmaceuticals and Human Serum.

Journal: Sensors (Basel, Switzerland)

Published: July 13, 2022

Innovative pulmonary targeting of terbutaline sulfate-laded novasomes for non-invasive tackling of asthma: statistical optimization and comparative in vitro/in vivo evaluation.

Innovative pulmonary targeting of terbutaline sulfate-laded novasomes for non-invasive tackling of asthma: statistical optimization and comparative in vitro/in vivo evaluation.

Journal: Drug delivery

Published: July 08, 2022

Intranasal Delivery of Granisetron to the Brain via Nanostructured Cubosomes-Based In Situ Gel for Improved Management of Chemotherapy-Induced Emesis.

Intranasal Delivery of Granisetron to the Brain via Nanostructured Cubosomes-Based In Situ Gel for Improved Management of Chemotherapy-Induced Emesis.

Journal: Pharmaceutics

Published: May 25, 2022

Lipid Nanocarriers Overlaid with Chitosan for Brain Delivery of Berberine via the Nasal Route.

Lipid Nanocarriers Overlaid with Chitosan for Brain Delivery of Berberine via the Nasal Route.

Journal: Pharmaceuticals (Basel, Switzerland)

Published: February 02, 2022

Surface-Modified Bilosomes Nanogel Bearing a Natural Plant Alkaloid for Safe Management of Rheumatoid Arthritis Inflammation.

Surface-Modified Bilosomes Nanogel Bearing a Natural Plant Alkaloid for Safe Management of Rheumatoid Arthritis Inflammation.

Journal: Pharmaceutics

Published: January 20, 2022

Showing 1-12 of 19

Last Updated: 09/26/2026