J A. Ratnayaka

MP 806, Tremona Road
Southampton, ENG SO166YD, United Kingdom

Last Updated: 09/26/2026

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Found 36 publications

Epigenetic-Mitochondrial-Metabolic Crosstalk in Retinal Pigment Epithelium (RPE) Dysfunction in Age-Related Macular Degeneration (AMD).

Epigenetic-Mitochondrial-Metabolic Crosstalk in Retinal Pigment Epithelium (RPE) Dysfunction in Age-Related Macular Degeneration (AMD).

Journal: Antioxidants (Basel, Switzerland)
Published: April 13, 2026

Effects of anti-obesity medications in the retina: a gathering storm or sunshine ahead?

Effects of anti-obesity medications in the retina: a gathering storm or sunshine ahead?

Journal: The British journal of ophthalmology
Published: December 11, 2025

Computational Approaches for Delineating Lysosomes and Related Intracellular Trafficking Vesicles in Confocal and Other Fluorescence Datasets.

Computational Approaches for Delineating Lysosomes and Related Intracellular Trafficking Vesicles in Confocal and Other Fluorescence Datasets.

Journal: Methods in molecular biology (Clifton, N.J.)
Published: July 21, 2025

Whole RNA-Seq Analysis Reveals Longitudinal Proteostasis Network Responses to Photoreceptor Outer Segment Trafficking and Degradation in RPE Cells.

Whole RNA-Seq Analysis Reveals Longitudinal Proteostasis Network Responses to Photoreceptor Outer Segment Trafficking and Degradation in RPE Cells.

Journal: Cells
Published: June 25, 2025

Functional polymorphisms in pigmentation-related genes MC1R and DCT display population-specific association with wet age-related macular degeneration.

Functional polymorphisms in pigmentation-related genes MC1R and DCT display population-specific association with wet age-related macular degeneration.

Journal: Biochemistry and biophysics reports
Published: April 17, 2025

Proportions of Basement Membrane Proteins in Cerebrovascular Smooth Muscle Cells After Exposure to Hypercapnia and Amyloid Beta.

Proportions of Basement Membrane Proteins in Cerebrovascular Smooth Muscle Cells After Exposure to Hypercapnia and Amyloid Beta.

Journal: Cells
Published: February 18, 2025

Sigma-2 receptor modulator CT1812 alters key pathways and rescues retinal pigment epithelium (RPE) functional deficits associated with dry age-related macular degeneration (AMD).

Sigma-2 receptor modulator CT1812 alters key pathways and rescues retinal pigment epithelium (RPE) functional deficits associated with dry age-related macular degeneration (AMD).

Journal: Scientific reports
Published: July 12, 2024

A longitudinal study of the 5xFAD mouse retina delineates Amyloid beta (Aβ)-mediated retinal pathology from age-related changes.

A longitudinal study of the 5xFAD mouse retina delineates Amyloid beta (Aβ)-mediated retinal pathology from age-related changes.

Journal: Alzheimer's research & therapy
Published: January 09, 2024

A high-throughput 3D X-ray histology facility for biomedical research and preclinical applications.

A high-throughput 3D X-ray histology facility for biomedical research and preclinical applications.

Journal: Wellcome open research
Published: November 06, 2023

Impaired lysosomes in the retinal pigment epithelium play a central role in the degeneration of the neuroretina.

Impaired lysosomes in the retinal pigment epithelium play a central role in the degeneration of the neuroretina.

Journal: Neural regeneration research
Published: July 14, 2023

Human equivalent doses of L-DOPA rescues retinal morphology and visual function in a murine model of albinism.

Human equivalent doses of L-DOPA rescues retinal morphology and visual function in a murine model of albinism.

Journal: Scientific reports
Published: May 24, 2023

A laser-induced mouse model of progressive retinal degeneration with central sparing displays features of parafoveal geographic atrophy.

A laser-induced mouse model of progressive retinal degeneration with central sparing displays features of parafoveal geographic atrophy.

Journal: Scientific reports
Published: December 13, 2022
Showing 1-12 of 36

Last Updated: 09/26/2026