Jacek Plewka

Krakow, MA 30387, Poland

Last Updated: 09/26/2026

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Found 40 publications

Novel Selenium-Containing Small Molecule PD-L1 Inhibitors: Design, Synthesis, and Evaluation of the Antitumor Activity.

Novel Selenium-Containing Small Molecule PD-L1 Inhibitors: Design, Synthesis, and Evaluation of the Antitumor Activity.

Journal: Journal of medicinal chemistry

Published: July 03, 2026

One Face, Three Solutions: Structural Convergence in PD-L1 Inhibition across Antibodies, Macrocycles, and Small Molecules.

One Face, Three Solutions: Structural Convergence in PD-L1 Inhibition across Antibodies, Macrocycles, and Small Molecules.

Journal: Journal of medicinal chemistry

Published: July 02, 2026

Immune Checkpoint-Based Therapies in Colorectal Cancer-Current Approaches and Future Perspectives.

Immune Checkpoint-Based Therapies in Colorectal Cancer-Current Approaches and Future Perspectives.

Journal: International journal of molecular sciences

Published: April 09, 2026

Glycosylation stabilizes TNFα and receptor complexes: structural and biophysical implications.

Glycosylation stabilizes TNFα and receptor complexes: structural and biophysical implications.

Journal: Carbohydrate research

Published: March 31, 2026

Coupling PD-L1 Inhibition and Lysosomal Degradation: Innovative Anti-PD-L1 Peptides for NSCLC Immunotherapy.

Coupling PD-L1 Inhibition and Lysosomal Degradation: Innovative Anti-PD-L1 Peptides for NSCLC Immunotherapy.

Journal: Journal of medicinal chemistry

Published: February 23, 2026

Discovery of natural product-derived rosavin as a programmed death-ligand 1 inhibitor for cancer immunotherapy.

Discovery of natural product-derived rosavin as a programmed death-ligand 1 inhibitor for cancer immunotherapy.

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology

Published: January 23, 2026

Crystallographic characterisation and development of bi-substrate inhibitors of coronavirus nsp14 methyltransferase.

Crystallographic characterisation and development of bi-substrate inhibitors of coronavirus nsp14 methyltransferase.

Journal: RSC medicinal chemistry

Published: October 08, 2025

Neutrophil extracellular traps formation driven by novel ELANE mutations in cyclic neutropenia patients.

Neutrophil extracellular traps formation driven by novel ELANE mutations in cyclic neutropenia patients.

Journal: Genes and immunity

Published: September 16, 2025

N-terphenylpicolinamide derivatives designed to target PD-L1 increase activation and proliferation of T cells, and their cytotoxic properties toward cancer cells.

N-terphenylpicolinamide derivatives designed to target PD-L1 increase activation and proliferation of T cells, and their cytotoxic properties toward cancer cells.

Journal: European journal of medicinal chemistry

Published: September 15, 2025

Characterization of Clinically Evaluated Small-Molecule Inhibitors of PD-L1 for Immunotherapy.

Characterization of Clinically Evaluated Small-Molecule Inhibitors of PD-L1 for Immunotherapy.

Journal: ACS medicinal chemistry letters

Published: April 27, 2025

Structural and Functional Characteristics of Potent Dioxygenase from Moesziomyces aphidis.

Structural and Functional Characteristics of Potent Dioxygenase from Moesziomyces aphidis.

Journal: JACS Au

Published: April 18, 2025

Correction: Musielak et al. CA-170 - A Potent Small-Molecule PD-L1 Inhibitor or Not? Molecules 2019, 24, 2804.

Correction: Musielak et al. CA-170 - A Potent Small-Molecule PD-L1 Inhibitor or Not? Molecules 2019, 24, 2804.

Journal: Molecules (Basel, Switzerland)

Published: March 21, 2025

Showing 1-12 of 40

Last Updated: 09/26/2026