Jack W. Houghton

Imperial College London 82 Wood Lane London W12 0BZ UK
London, ENG W120BZ, United Kingdom

Last Updated: 09/26/2026

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Found 25 publications

Proteome-wide target profiling of α-helix mimetics.

Proteome-wide target profiling of α-helix mimetics.

Journal: RSC chemical biology
Published: February 16, 2026

Optimized Sample Handling Minimizes Peptide Adsorption to Plastics to Enable High Sensitivity Evosep Based Chemical Proteomics.

Optimized Sample Handling Minimizes Peptide Adsorption to Plastics to Enable High Sensitivity Evosep Based Chemical Proteomics.

Journal: Proteomics
Published: October 13, 2025

Electrophilic compound screening identifies GPX4-dependent ferroptosis as a senescence vulnerability.

Electrophilic compound screening identifies GPX4-dependent ferroptosis as a senescence vulnerability.

Journal: Nature cell biology
Published: September 10, 2025

MYC deregulation sensitizes cancer cells to N-myristoyltransferase inhibition.

MYC deregulation sensitizes cancer cells to N-myristoyltransferase inhibition.

Journal: Cell reports
Published: June 25, 2025

Identification and characterization of nanobodies specific for the human ubiquitin-like ISG15 protein.

Identification and characterization of nanobodies specific for the human ubiquitin-like ISG15 protein.

Journal: The Journal of biological chemistry
Published: June 22, 2025

Selective N-Terminal Modification of Peptides and Proteins Using Fatty Acyl Phosphates.

Selective N-Terminal Modification of Peptides and Proteins Using Fatty Acyl Phosphates.

Journal: Angewandte Chemie (International ed. in English)
Published: June 17, 2025

Affinity-based protein profiling of MDM2 inhibitor Navtemadlin.

Affinity-based protein profiling of MDM2 inhibitor Navtemadlin.

Journal: Chemical science
Published: January 07, 2025

Spatiotemporally resolved GPCR interactome uncovers unique mediators of receptor agonism.

Spatiotemporally resolved GPCR interactome uncovers unique mediators of receptor agonism.

Journal: Cell chemical biology
Published: June 21, 2024

A multiparametric anti-aging CRISPR screen uncovers a role for BAF in protein synthesis regulation.

A multiparametric anti-aging CRISPR screen uncovers a role for BAF in protein synthesis regulation.

Journal: Nature communications
Published: July 31, 2023

Salivary peptidome analysis and protease prediction during orthodontic treatment with fixed appliances.

Salivary peptidome analysis and protease prediction during orthodontic treatment with fixed appliances.

Journal: Scientific reports
Published: October 05, 2022

The exocyst complex is an essential component of the mammalian constitutive secretory pathway.

The exocyst complex is an essential component of the mammalian constitutive secretory pathway.

Journal: The Journal of cell biology
Published: May 31, 2022

A palmitoyl transferase chemical-genetic system to map ZDHHC-specific S-acylation.

A palmitoyl transferase chemical-genetic system to map ZDHHC-specific S-acylation.

Journal: Nature biotechnology
Published: May 25, 2022
Showing 1-12 of 25

Last Updated: 09/26/2026