Jacques Le Seyec

Rennes, France

Last Updated: 09/26/2026

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Found 19 publications

MLKL in liver parenchymal cells promotes liver cancer in murine metabolic dysfunction-associated steatotic liver disease.

MLKL in liver parenchymal cells promotes liver cancer in murine metabolic dysfunction-associated steatotic liver disease.

Journal: Cell death & disease

Published: April 03, 2025

Trim21 deficiency in mice increases HCC carcinogenesis in a NASH context and is associated with immune checkpoint upregulation.

Trim21 deficiency in mice increases HCC carcinogenesis in a NASH context and is associated with immune checkpoint upregulation.

Journal: International journal of cancer

Published: July 12, 2023

RIPK1 in Liver Parenchymal Cells Limits Murine Hepatitis during Acute CCl4-Induced Liver Injury.

RIPK1 in Liver Parenchymal Cells Limits Murine Hepatitis during Acute CCl4-Induced Liver Injury.

Journal: International journal of molecular sciences

Published: May 06, 2022

Switching to Regular Diet Partially Resolves Liver Fibrosis Induced by High-Fat, High-Cholesterol Diet in Mice.

Switching to Regular Diet Partially Resolves Liver Fibrosis Induced by High-Fat, High-Cholesterol Diet in Mice.

Journal: Nutrients

Published: December 07, 2021

Questioning the RIPK1 kinase activity involvement in acetaminophen-induced hepatotoxicity in mouse.

Questioning the RIPK1 kinase activity involvement in acetaminophen-induced hepatotoxicity in mouse.

Journal: Free radical biology & medicine

Published: September 02, 2021

Receptor-interacting protein kinase-1 ablation in liver parenchymal cells promotes liver fibrosis in murine NASH without affecting other symptoms.

Receptor-interacting protein kinase-1 ablation in liver parenchymal cells promotes liver fibrosis in murine NASH without affecting other symptoms.

Journal: Journal of molecular medicine (Berlin, Germany)

Published: April 08, 2021

TRIM21, a New Component of the TRAIL-Induced Endogenous Necrosome Complex.

TRIM21, a New Component of the TRAIL-Induced Endogenous Necrosome Complex.

Journal: Frontiers in molecular biosciences

Published: December 22, 2020

Intrahepatocytic necroptosis is dispensable for hepatocyte death in murine immune-mediated hepatitis.

Intrahepatocytic necroptosis is dispensable for hepatocyte death in murine immune-mediated hepatitis.

Journal: Journal of hepatology

Published: April 22, 2020

Hepatocellular Carcinoma Emergence in Diabetic Mice with Non-Alcoholic Steatohepatitis Depends on Diet and Is Delayed in Liver Exhibiting an Active Immune Response.

Hepatocellular Carcinoma Emergence in Diabetic Mice with Non-Alcoholic Steatohepatitis Depends on Diet and Is Delayed in Liver Exhibiting an Active Immune Response.

Journal: Cancers

Published: April 14, 2020

Depletion of RIPK1 in hepatocytes exacerbates liver damage in fulminant viral hepatitis.

Depletion of RIPK1 in hepatocytes exacerbates liver damage in fulminant viral hepatitis.

Journal: Cell death & disease

Published: July 31, 2018

RIPK1 protects hepatocytes from death in Fas-induced hepatitis.

RIPK1 protects hepatocytes from death in Fas-induced hepatitis.

Journal: Scientific reports

Published: May 09, 2017

Endogenous IL-33 Deficiency Exacerbates Liver Injury and Increases Hepatic Influx of Neutrophils in Acute Murine Viral Hepatitis.

Endogenous IL-33 Deficiency Exacerbates Liver Injury and Increases Hepatic Influx of Neutrophils in Acute Murine Viral Hepatitis.

Journal: Mediators of inflammation

Published: October 17, 2016

Showing 1-12 of 19

Last Updated: 09/26/2026