Jaehoon K. Sim

Seoul, Republic of Korea

Last Updated: 09/26/2026

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Found 37 publications

Discovery of novel pyrazolo[3,4-d]pyrimidine-6-amine derivatives as potent polo-like kinase 2 inhibitors.

Discovery of novel pyrazolo[3,4-d]pyrimidine-6-amine derivatives as potent polo-like kinase 2 inhibitors.

Journal: European journal of medicinal chemistry

Published: May 12, 2026

Non-invasive classification of coronary perfusion pressure during CPR using smartphone-based skin video and deep learning.

Non-invasive classification of coronary perfusion pressure during CPR using smartphone-based skin video and deep learning.

Journal: Computer methods and programs in biomedicine

Published: July 14, 2025

Natural products targeting the metabolism of amino acids: from discovery to synthetic development.

Natural products targeting the metabolism of amino acids: from discovery to synthetic development.

Journal: Natural product reports

Published: July 11, 2025

One-step synthesis of 2-arylindoles from indolines via Pd-catalyzed oxidative dehydrogenation and C2-selective arylation.

One-step synthesis of 2-arylindoles from indolines via Pd-catalyzed oxidative dehydrogenation and C2-selective arylation.

Journal: RSC advances

Published: June 30, 2025

Discovery of Cyclopentane-Based Phospholipids as Miltefosine Analogs with Superior Potency and Enhanced Selectivity Against Naegleria fowleri.

Discovery of Cyclopentane-Based Phospholipids as Miltefosine Analogs with Superior Potency and Enhanced Selectivity Against Naegleria fowleri.

Journal: Pharmaceuticals (Basel, Switzerland)

Published: June 04, 2025

Photoinduced Site-Selective Alkylation Enabling Synthesis of C-3-Alkylated Quinoxalinone on DNA.

Photoinduced Site-Selective Alkylation Enabling Synthesis of C-3-Alkylated Quinoxalinone on DNA.

Journal: Organic letters

Published: April 30, 2025

Exploring MAO inhibitory activity of 5-hydroxy regioisomers of hispidol's analogs leads to identification of novel highly selective MAO-B open-conformation inhibitors.

Exploring MAO inhibitory activity of 5-hydroxy regioisomers of hispidol's analogs leads to identification of novel highly selective MAO-B open-conformation inhibitors.

Journal: Molecular diversity

Published: March 11, 2025

Design, synthesis and evaluation of acetylcholine-antitumor lipid hybrids led to identification of a potential anticancer agent disrupting the CDK4/6-Rb pathway in lung cancer.

Design, synthesis and evaluation of acetylcholine-antitumor lipid hybrids led to identification of a potential anticancer agent disrupting the CDK4/6-Rb pathway in lung cancer.

Journal: RSC medicinal chemistry

Published: December 18, 2024

Determination of cardiopulmonary resuscitation quality based on machine learning algorithms using various biological signals.

Determination of cardiopulmonary resuscitation quality based on machine learning algorithms using various biological signals.

Journal: Health information science and systems

Published: December 12, 2024

Hot-Melt Extrusion Drug Delivery System-Formulated Haematococcus pluvialis Extracts Regulate Inflammation and Oxidative Stress in Lipopolysaccharide-Stimulated Macrophages.

Hot-Melt Extrusion Drug Delivery System-Formulated Haematococcus pluvialis Extracts Regulate Inflammation and Oxidative Stress in Lipopolysaccharide-Stimulated Macrophages.

Journal: Marine drugs

Published: October 03, 2024

Development of artificial intelligence-driven biosignal-sensitive cardiopulmonary resuscitation robot.

Development of artificial intelligence-driven biosignal-sensitive cardiopulmonary resuscitation robot.

Journal: Resuscitation

Published: May 12, 2024

Variable Stiffness and Damping Mechanism for CPR Manikin to Simulate Mechanical Properties of Human Chest.

Variable Stiffness and Damping Mechanism for CPR Manikin to Simulate Mechanical Properties of Human Chest.

Journal: IEEE journal of translational engineering in health and medicine

Published: February 19, 2024

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Last Updated: 09/26/2026