Jalila Chagraoui

Montreal, QC, Canada

Last Updated: 09/26/2026

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Found 35 publications

TP53-mutant AML with ribosomal gene loss exhibits impaired protein translation and sensitivity to HSP90 inhibition.

TP53-mutant AML with ribosomal gene loss exhibits impaired protein translation and sensitivity to HSP90 inhibition.

Journal: Science advances
Published: May 15, 2026

CoREST in pieces: Dismantling the CoREST complex for cancer therapy and beyond.

CoREST in pieces: Dismantling the CoREST complex for cancer therapy and beyond.

Journal: Science advances
Published: June 06, 2025

CD33 epitope editing unlocks UM171-expanded cord blood grafts for AML immunotherapy.

CD33 epitope editing unlocks UM171-expanded cord blood grafts for AML immunotherapy.

Journal: Molecular therapy : the journal of the American Society of Gene Therapy
Published: April 24, 2025

IL1RAP is an immunotherapeutic target for normal karyotype triple-mutated acute myeloid leukemia.

IL1RAP is an immunotherapeutic target for normal karyotype triple-mutated acute myeloid leukemia.

Journal: Biomarker research
Published: November 06, 2024

DDB1 engagement defines the selectivity of S656 analogs for cyclin K degradation over CDK inhibition.

DDB1 engagement defines the selectivity of S656 analogs for cyclin K degradation over CDK inhibition.

Journal: EMBO reports
Published: October 09, 2024

Deciphering the effect of UM171 on human hematopoietic progenitor cell fate through clonal analysis.

Deciphering the effect of UM171 on human hematopoietic progenitor cell fate through clonal analysis.

Journal: Nature communications
Published: April 17, 2024

Immunotherapeutic targeting of surfaceome heterogeneity in AML.

Immunotherapeutic targeting of surfaceome heterogeneity in AML.

Journal: Cell reports
Published: October 05, 2023

KBTBD4-mediated reduction of MYC is critical for hematopoietic stem cell expansion upon UM171 treatment.

KBTBD4-mediated reduction of MYC is critical for hematopoietic stem cell expansion upon UM171 treatment.

Journal: Blood
Published: May 30, 2023

DELE1 haploinsufficiency causes resistance to mitochondrial stress-induced apoptosis in monosomy 5/del(5q) AML.

DELE1 haploinsufficiency causes resistance to mitochondrial stress-induced apoptosis in monosomy 5/del(5q) AML.

Journal: Leukemia
Published: May 29, 2023

Towards clinically meaningful expansion of human HSCs.

Towards clinically meaningful expansion of human HSCs.

Journal: Cell research
Published: May 10, 2023

CBFA2T3::GLIS2 pediatric acute megakaryoblastic leukemia is sensitive to BCL-XL inhibition by navitoclax and DT2216.

CBFA2T3::GLIS2 pediatric acute megakaryoblastic leukemia is sensitive to BCL-XL inhibition by navitoclax and DT2216.

Journal: Blood advances
Published: September 08, 2022

CEACAM1 is a novel culture-compatible surface marker of expanded long-term reconstituting hematopoietic stem cells.

CEACAM1 is a novel culture-compatible surface marker of expanded long-term reconstituting hematopoietic stem cells.

Journal: Blood advances
Published: December 17, 2021
Showing 1-12 of 35

Last Updated: 09/26/2026