James A. Decaprio

Oncology
450 Brookline Ave
Boston, MA 02215

Last Updated: 09/26/2026

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Found 94 publications

Dual CDK2 and CDK4/6 inhibition suppresses Rb/E2F signaling and enhances anti-leukemic activity in acute myeloid leukemia.

Dual CDK2 and CDK4/6 inhibition suppresses Rb/E2F signaling and enhances anti-leukemic activity in acute myeloid leukemia.

Journal: Haematologica
Published: February 17, 2026

Targeted degradation of MDM2 overcomes feedback regulation of p53 signaling in Merkel cell carcinoma models.

Targeted degradation of MDM2 overcomes feedback regulation of p53 signaling in Merkel cell carcinoma models.

Journal: The Journal of clinical investigation
Published: August 11, 2025

PRMT5 inhibition disrupts detained intron splicing and impairs ATR signaling with increased DNA damage.

PRMT5 inhibition disrupts detained intron splicing and impairs ATR signaling with increased DNA damage.

Journal: Communications biology
Published: July 23, 2025

High tumor mutational burden and PIK3CA mutations correlate with poor Merkel cell carcinoma-specific survival.

High tumor mutational burden and PIK3CA mutations correlate with poor Merkel cell carcinoma-specific survival.

Journal: JCI insight
Published: July 22, 2025

Challenges of Treating Merkel Cell Carcinoma in Brazil.

Challenges of Treating Merkel Cell Carcinoma in Brazil.

Journal: Journal of surgical oncology
Published: January 07, 2025

IMPDH inhibition induces DNA replication stress and ATR sensitivity in Merkel cell carcinoma.

IMPDH inhibition induces DNA replication stress and ATR sensitivity in Merkel cell carcinoma.

Journal: iScience
Published: September 25, 2024

BPDCN MYB fusions regulate cell cycle genes, impair differentiation, and induce myeloid-dendritic cell leukemia.

BPDCN MYB fusions regulate cell cycle genes, impair differentiation, and induce myeloid-dendritic cell leukemia.

Journal: JCI insight
Published: June 13, 2024

APC/C and SCFcyclin F Constitute a Reciprocal Feedback Circuit Controlling S-Phase Entry.

APC/C and SCFcyclin F Constitute a Reciprocal Feedback Circuit Controlling S-Phase Entry.

Journal: Cell reports
Published: March 08, 2024

Tumor cell-intrinsic PD-1 promotes Merkel cell carcinoma growth by activating downstream mTOR-mitochondrial ROS signaling.

Tumor cell-intrinsic PD-1 promotes Merkel cell carcinoma growth by activating downstream mTOR-mitochondrial ROS signaling.

Journal: Science advances
Published: January 19, 2024

Why do we distinguish between virus-positive and virus-negative Merkel cell carcinoma?

Why do we distinguish between virus-positive and virus-negative Merkel cell carcinoma?

Journal: The British journal of dermatology
Published: January 18, 2024

Author Correction: Liquid biopsy epigenomic profiling for cancer subtyping.

Author Correction: Liquid biopsy epigenomic profiling for cancer subtyping.

Journal: Nature medicine
Published: December 04, 2023

Integrative analysis reveals therapeutic potential of pyrvinium pamoate in Merkel cell carcinoma.

Integrative analysis reveals therapeutic potential of pyrvinium pamoate in Merkel cell carcinoma.

Journal: The Journal of clinical investigation
Published: November 29, 2023
Showing 1-12 of 94

Last Updated: 09/26/2026